From squid giant axon to automated patch-clamp: electrophysiology in venom and antivenom research

From squid giant axon to automated patch-clamp: electrophysiology in venom and antivenom research

Ion channels play a crucial role in diverse physiological processes, including neurotransmission and muscle contraction. Venomous creatures exploit the vital function of ion channels by producing toxins in their venoms that specifically target these ion channels to facilitate prey capture upon a bit...

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Bibliographic Details
Main Authors: Shirin Ahmadi, Melisa Benard-Valle, Kim Boddum, Fernanda C. Cardoso, Glenn F. King, Andreas Hougaard Laustsen, Anne Ljungars
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Pharmacology
Subjects:
electrophysiology
patch-clamp
ion channel
venom
antivenom
drug discovery
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1249336/full

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