Tissue Nonspecific Alkaline Phosphatase Function in Bone and Muscle Progenitor Cells: Control of Mitochondrial Respiration and ATP Production

Tissue Nonspecific Alkaline Phosphatase Function in Bone and Muscle Progenitor Cells: Control of Mitochondrial Respiration and ATP Production

Tissue nonspecific alkaline phosphatase (TNAP/<i>Alpl</i>) is associated with cell stemness; however, the function of TNAP in mesenchymal progenitor cells remains largely unknown. In this study, we aimed to establish an essential role for TNAP in bone and muscle progenitor cells. We inve...

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Bibliographic Details
Main Authors: Zhi Zhang, Hwa Kyung Nam, Spencer Crouch, Nan E. Hatch
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
tissue nonspecific alkaline phosphatase
mitochondria
bone marrow stromal cell
bone
muscle
nucleotide adenosine triphosphate
Online Access:https://www.mdpi.com/1422-0067/22/3/1140

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