Thiamine Deficiency Neuropathy in a Patient with Malnutrition due to Melancholic Depression
Introduction. Melancholic depression is a daily clinical reality in psychiatry. It is a therapeutic emergency that can jeopardize life if not promptly and adequately treated. Apart from its high suicidal risk, complications related to the under-nourishment state are to be feared. Case Presentation....
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| Format: | Article |
| Language: | English |
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Hindawi Limited
2024-01-01
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| Series: | Case Reports in Psychiatry |
| Online Access: | http://dx.doi.org/10.1155/2024/1797983 |
| _version_ | 1797260525345701888 |
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| author | Rihene Melki Rim Ben Soussia Houcem Elomma Mrabet Walid Bouali Lazhar Zarrouk |
| author_facet | Rihene Melki Rim Ben Soussia Houcem Elomma Mrabet Walid Bouali Lazhar Zarrouk |
| author_sort | Rihene Melki |
| collection | DOAJ |
| description | Introduction. Melancholic depression is a daily clinical reality in psychiatry. It is a therapeutic emergency that can jeopardize life if not promptly and adequately treated. Apart from its high suicidal risk, complications related to the under-nourishment state are to be feared. Case Presentation. A 36-year-old woman was admitted with depressive symptoms, significant weight loss, and total functional impotence. Laboratory investigations revealed severe thiamine (vitamin B1) deficiency. An electromyography confirmed a sensory axonal neuropathy involving all four extremities suggesting a deficiency origin. Discussion. Vitamin and mineral deficiencies have been described in patients with malnutrition resulting from psychiatric illness (anorexia nervosa, eating disorders, severe depression, etc.). Thiamine is an essential cofactor in several biochemical pathways. Its deficiency can lead to neuropsychiatric morbidity. Conclusion. In our case, the rapid weight loss facilitated a cascade of complications related to nutritional deficiencies. Based on our clinical observations and the literature, thiamine deficiency should be considered in the presence of malnutrition and vulnerability, both on an organic and psychiatric level. |
| first_indexed | 2024-04-24T23:26:42Z |
| format | Article |
| id | doaj.art-0fe00aefa8fe41d38037c4a6a22a8026 |
| institution | Directory Open Access Journal |
| issn | 2090-6838 |
| language | English |
| last_indexed | 2024-04-24T23:26:42Z |
| publishDate | 2024-01-01 |
| publisher | Hindawi Limited |
| record_format | Article |
| series | Case Reports in Psychiatry |
| spelling | doaj.art-0fe00aefa8fe41d38037c4a6a22a80262024-03-16T00:00:02ZengHindawi LimitedCase Reports in Psychiatry2090-68382024-01-01202410.1155/2024/1797983Thiamine Deficiency Neuropathy in a Patient with Malnutrition due to Melancholic DepressionRihene Melki0Rim Ben Soussia1Houcem Elomma Mrabet2Walid Bouali3Lazhar Zarrouk4Psychiatry DepartmentPsychiatry DepartmentInternal Medicine and Endocrinology DepartmentPsychiatry DepartmentPsychiatry DepartmentIntroduction. Melancholic depression is a daily clinical reality in psychiatry. It is a therapeutic emergency that can jeopardize life if not promptly and adequately treated. Apart from its high suicidal risk, complications related to the under-nourishment state are to be feared. Case Presentation. A 36-year-old woman was admitted with depressive symptoms, significant weight loss, and total functional impotence. Laboratory investigations revealed severe thiamine (vitamin B1) deficiency. An electromyography confirmed a sensory axonal neuropathy involving all four extremities suggesting a deficiency origin. Discussion. Vitamin and mineral deficiencies have been described in patients with malnutrition resulting from psychiatric illness (anorexia nervosa, eating disorders, severe depression, etc.). Thiamine is an essential cofactor in several biochemical pathways. Its deficiency can lead to neuropsychiatric morbidity. Conclusion. In our case, the rapid weight loss facilitated a cascade of complications related to nutritional deficiencies. Based on our clinical observations and the literature, thiamine deficiency should be considered in the presence of malnutrition and vulnerability, both on an organic and psychiatric level.http://dx.doi.org/10.1155/2024/1797983 |
| spellingShingle | Rihene Melki Rim Ben Soussia Houcem Elomma Mrabet Walid Bouali Lazhar Zarrouk Thiamine Deficiency Neuropathy in a Patient with Malnutrition due to Melancholic Depression Case Reports in Psychiatry |
| title | Thiamine Deficiency Neuropathy in a Patient with Malnutrition due to Melancholic Depression |
| title_full | Thiamine Deficiency Neuropathy in a Patient with Malnutrition due to Melancholic Depression |
| title_fullStr | Thiamine Deficiency Neuropathy in a Patient with Malnutrition due to Melancholic Depression |
| title_full_unstemmed | Thiamine Deficiency Neuropathy in a Patient with Malnutrition due to Melancholic Depression |
| title_short | Thiamine Deficiency Neuropathy in a Patient with Malnutrition due to Melancholic Depression |
| title_sort | thiamine deficiency neuropathy in a patient with malnutrition due to melancholic depression |
| url | http://dx.doi.org/10.1155/2024/1797983 |
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