Local Microbubble Removal in Polydimethylsiloxane Microchannel by Balancing Negative and Atmospheric Pressures

Long-term experiments using organoids and tissues are crucial for drug development. Microfluidic devices have been regularly used in long-term experiments. However, microbubbles often form in these devices, and they may damage and starve cells. A method involving the application of negative pressure...

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Bibliographic Details
Main Authors: Yasunori Tokuoka, Tadashi Ishida
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Micromachines
Subjects:
Online Access:https://www.mdpi.com/2072-666X/15/1/37