TNF Receptor 1 Promotes Early-Life Immunity and Protects against Colitis in Mice

TNF Receptor 1 Promotes Early-Life Immunity and Protects against Colitis in Mice

Summary: Neutralization of tumor necrosis factor (TNF) represents a widely used therapeutic strategy for autoimmune diseases including inflammatory bowel disease (IBD). However, the fact that many patients with IBD are non-responsive to anti-TNF therapies suggests the need for a better understanding...

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Bibliographic Details
Main Authors: Cambrian Y. Liu, Sharon S. Tam, Ying Huang, Philip E. Dubé, Rabea Alhosh, Nandini Girish, Shivesh Punit, Shirin Nataneli, Fan Li, Jeffrey M. Bender, M. Kay Washington, D. Brent Polk
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:Cell Reports
Subjects:
IBD
microbiome
antibiotics
barrier
weaning reaction
mucosa
Online Access:http://www.sciencedirect.com/science/article/pii/S221112472031264X

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