Evaluation of Correlation between Salivary Calcium, Alkaline Phosphatase and Osteoporosis- A Prospective, Comparative and Observational Study
Introduction: Fixed and/or removable prosthodontics caters to the restorative needs of the largest count of geriatric patients whose rehabilitative procedures depend on the quality and quantity of available bone. The common diagnostic parameters for quantifying bone may involve an invasive blood...
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Private Limited
2017-03-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://jcdr.net/articles/PDF/9583/24960_CE[Ra1]_F(DK)_PF1(VG_RK)_PFA(P)_PF2(P_NESY).pdf |
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| author | Mainak Kanti Saha Prerna Agrawal Suparna Ganguly Saha Vinod Vishwanathan Vandana Pathak Sakuru Venkata Saiprasad Purvi Dhariwal Mahendra Dave |
| author_facet | Mainak Kanti Saha Prerna Agrawal Suparna Ganguly Saha Vinod Vishwanathan Vandana Pathak Sakuru Venkata Saiprasad Purvi Dhariwal Mahendra Dave |
| author_sort | Mainak Kanti Saha |
| collection | DOAJ |
| description | Introduction: Fixed and/or removable prosthodontics caters to
the restorative needs of the largest count of geriatric patients
whose rehabilitative procedures depend on the quality and
quantity of available bone. The common diagnostic parameters
for quantifying bone may involve an invasive blood examination,
an expensive bone densitometry procedure or a urine analysis.
Sialometry involving the basic biochemistry of saliva analysis may
be proposed as an alternative to the conventional investigative
protocol and its usefulness may be attributed owing to its non
invasive and simpler procedure.
Aim: The aim of this study was to compare the salivary calcium
and alkaline phosphatase among osteoporotic, osteopenic and
normal edentulous subjects.
Materials and Methods: A prospective, comparative and
observational study was carried out on 80 selected edentulous
subjects (40 males and 40 females) aged 55-75 years (30
osteoporotic, 30 osteopenic and 20 control). A sample of saliva
was taken for the study. Salivary calcium was measured by
Arsenazo reaction; and alkaline phosphatase by the International
Federation of Clinical Chemistry (IFCC) method. Statistical
analysis was done by unpaired t-test. A comparison was made
in the levels of salivary calcium and alkaline phosphatase with
that of osteoporosis and osteopenia.
Results: The mean salivary calcium and alkaline phosphatase
levels were found to be significantly higher in the osteoporotic
and osteopenic edentulous subjects as compared to the control
group.
Conclusion: Salivary calcium and alkaline phosphatase are
increased significantly in case of osteoporosis and osteopenia.
Hence, screening of salivary samples of patients may be an
effective indicator for the detection of underlying disorders of
bone metabolism. |
| first_indexed | 2024-12-11T13:53:45Z |
| format | Article |
| id | doaj.art-0fe92fba59124b4e9acf12d2628fc093 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-12-11T13:53:45Z |
| publishDate | 2017-03-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-0fe92fba59124b4e9acf12d2628fc0932022-12-22T01:04:08ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2017-03-01113ZC63ZC6610.7860/JCDR/2017/24960.9583Evaluation of Correlation between Salivary Calcium, Alkaline Phosphatase and Osteoporosis- A Prospective, Comparative and Observational StudyMainak Kanti Saha0Prerna Agrawal1Suparna Ganguly Saha2Vinod Vishwanathan3Vandana Pathak4Sakuru Venkata Saiprasad5Purvi Dhariwal6Mahendra Dave7Professor and Head, Department of Prosthodontics, College of Dental Science and Hospital, Indore, Madhya Pradesh, India.Postgraduate Student, Department of Prosthodontics, College of Dental Science and Hospital, Pithampur, Madhya Pradesh, India.Professor and Head, Department of Conservative Dentistry, College of Dental Science and Hospital, Indore, Madhya Pradesh, India.Reader, Department of Prosthodontics, College of Dental Science and Hospital, Indore, Madhya Pradesh, India.Senior Lecturer, Department of Prosthodontics, College of Dental Science and Hospital, Indore, Madhya Pradesh, India.Principal Scientist, Indian Council of Agricultural Research, Indian Agricultural Research Institute, Indore, Madhya Pradesh, India.Postgraduate Student, Department of Prosthodontics, College of Dental Science and Hospital, Indore, Madhya Pradesh, India.Postgraduate Student, Department of Prosthodontics, College of Dental Science and Hospital, Indore, Madhya Pradesh, India.Introduction: Fixed and/or removable prosthodontics caters to the restorative needs of the largest count of geriatric patients whose rehabilitative procedures depend on the quality and quantity of available bone. The common diagnostic parameters for quantifying bone may involve an invasive blood examination, an expensive bone densitometry procedure or a urine analysis. Sialometry involving the basic biochemistry of saliva analysis may be proposed as an alternative to the conventional investigative protocol and its usefulness may be attributed owing to its non invasive and simpler procedure. Aim: The aim of this study was to compare the salivary calcium and alkaline phosphatase among osteoporotic, osteopenic and normal edentulous subjects. Materials and Methods: A prospective, comparative and observational study was carried out on 80 selected edentulous subjects (40 males and 40 females) aged 55-75 years (30 osteoporotic, 30 osteopenic and 20 control). A sample of saliva was taken for the study. Salivary calcium was measured by Arsenazo reaction; and alkaline phosphatase by the International Federation of Clinical Chemistry (IFCC) method. Statistical analysis was done by unpaired t-test. A comparison was made in the levels of salivary calcium and alkaline phosphatase with that of osteoporosis and osteopenia. Results: The mean salivary calcium and alkaline phosphatase levels were found to be significantly higher in the osteoporotic and osteopenic edentulous subjects as compared to the control group. Conclusion: Salivary calcium and alkaline phosphatase are increased significantly in case of osteoporosis and osteopenia. Hence, screening of salivary samples of patients may be an effective indicator for the detection of underlying disorders of bone metabolism.https://jcdr.net/articles/PDF/9583/24960_CE[Ra1]_F(DK)_PF1(VG_RK)_PFA(P)_PF2(P_NESY).pdfedentulous patientosteoporotic patientssalivary analysisscreening |
| spellingShingle | Mainak Kanti Saha Prerna Agrawal Suparna Ganguly Saha Vinod Vishwanathan Vandana Pathak Sakuru Venkata Saiprasad Purvi Dhariwal Mahendra Dave Evaluation of Correlation between Salivary Calcium, Alkaline Phosphatase and Osteoporosis- A Prospective, Comparative and Observational Study Journal of Clinical and Diagnostic Research edentulous patient osteoporotic patients salivary analysis screening |
| title | Evaluation of Correlation between Salivary Calcium, Alkaline Phosphatase and Osteoporosis- A Prospective, Comparative and Observational Study |
| title_full | Evaluation of Correlation between Salivary Calcium, Alkaline Phosphatase and Osteoporosis- A Prospective, Comparative and Observational Study |
| title_fullStr | Evaluation of Correlation between Salivary Calcium, Alkaline Phosphatase and Osteoporosis- A Prospective, Comparative and Observational Study |
| title_full_unstemmed | Evaluation of Correlation between Salivary Calcium, Alkaline Phosphatase and Osteoporosis- A Prospective, Comparative and Observational Study |
| title_short | Evaluation of Correlation between Salivary Calcium, Alkaline Phosphatase and Osteoporosis- A Prospective, Comparative and Observational Study |
| title_sort | evaluation of correlation between salivary calcium alkaline phosphatase and osteoporosis a prospective comparative and observational study |
| topic | edentulous patient osteoporotic patients salivary analysis screening |
| url | https://jcdr.net/articles/PDF/9583/24960_CE[Ra1]_F(DK)_PF1(VG_RK)_PFA(P)_PF2(P_NESY).pdf |
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