Intra-articular injection of platelet lysate-derived extracellular vesicles recovers from knee osteoarthritis in an in vivo rat model

Intra-articular injection of platelet lysate-derived extracellular vesicles recovers from knee osteoarthritis in an in vivo rat model

Objective: MSCs and Platelet-Rich Plasma are the main focus in the study of new regenerative treatments aimed to reverse Osteoarthritis (OA). However, extracellular vesicles (EVs) present several advantages to cell-based treatments. Thus, the aim of this study was to compare and evaluate the regener...

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Bibliographic Details
Main Authors:	Maria Antònia Forteza-Genestra, Miquel Antich-Rosselló, Carmen Ráez-Meseguer, Anna Tomàs Sangenís, Javier Calvo, Antoni Gayà, Marta Monjo, Joana Maria Ramis
Format:	Article
Language:	English
Published:	Elsevier 2024-03-01
Series:	Journal of Orthopaedic Translation
Subjects:	Extracellular vesicles Knee OA in vivo model Mesenchymal stromal cells Osteoarthritis Platelet lysate
Online Access:	http://www.sciencedirect.com/science/article/pii/S2214031X23000797

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