Prevalence of Panton-Valentine Leukocidin (PVL) and Antimicrobial Resistance in Community-Acquired Clinical Staphylococcus aureus in an Urban Gambian Hospital: A 11-Year Period Retrospective Pilot Study

Prevalence of Panton-Valentine Leukocidin (PVL) and Antimicrobial Resistance in Community-Acquired Clinical Staphylococcus aureus in an Urban Gambian Hospital: A 11-Year Period Retrospective Pilot Study

Background:Staphylococcus aureus is a major human pathogen. Panton-Valentine leukocidin (PVL) is a virulence factor produced by some strains that causes leukocyte lysis and tissue necrosis. PVL-associated S. aureus (PVL-SA) predominantly causes skin and soft-tissue infections (SSTIs) but can also ca...

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Main Authors: Saffiatou Darboe, Sarah Dobreniecki, Sheikh Jarju, Mamadou Jallow, Nuredin Ibrahim Mohammed, Miriam Wathuo, Buntung Ceesay, Sam Tweed, Robindra Basu Roy, Uduak Okomo, Brenda Kwambana-Adams, Martin Antonio, Richard S. Bradbury, Thushan I. de Silva, Karen Forrest, Anna Roca, Bolarinde Joseph Lawal, Davis Nwakanma, Ousman Secka
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Panton-Valentine leukocidin
Staphylococcus aureus
community-acquired
antimicrobial resistance
The Gambia
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2019.00170/full

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