Low-Noise Potentiostat Readout Circuit with a Chopper Fully Differential Difference Amplifier for Glucose Monitoring
This paper presents a low-noise potentiostat readout circuit with a chopper fully differential difference amplifier (FDDA) for glucose monitoring. Glucose monitoring is necessary for the early diagnosis of diabetes complications and for health management. Ammeter electrochemical sensors are widely u...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-11-01
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| Series: | Applied Sciences |
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| Online Access: | https://www.mdpi.com/2076-3417/12/22/11334 |
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| author | Gyuri Choi Kyeongsik Nam Mookyoung Yoo Sanggyun Kang Byeongkwan Jin Kyounghwan Kim Hyeoktae Son Hyoungho Ko |
| author_facet | Gyuri Choi Kyeongsik Nam Mookyoung Yoo Sanggyun Kang Byeongkwan Jin Kyounghwan Kim Hyeoktae Son Hyoungho Ko |
| author_sort | Gyuri Choi |
| collection | DOAJ |
| description | This paper presents a low-noise potentiostat readout circuit with a chopper fully differential difference amplifier (FDDA) for glucose monitoring. Glucose monitoring is necessary for the early diagnosis of diabetes complications and for health management. Ammeter electrochemical sensors are widely used for glucose detection, and in general, a three-electrode structure of a reference electrode (RE), a counter electrode (CE), and a working electrode (WE) is implemented with a potentiostat structure. A low-noise characteristic of the readout circuit is essential for highly accurate glucose monitoring. The chopping technique can reduce low-frequency noises such as 1/f noise and can achieve the required low-noise characteristic. The proposed potentiostat readout circuit is based on a low-noise chopper FDDA with a class-AB output stage. The implementation of the chopper FDDA scheme of the potentiostat readout circuit can decrease the number of amplifiers in the control part of the potentiostat, with reduced power consumption and a wide dynamic output range. The negative feedback loop of the inverting amplifier scheme with the FDDA maintains the voltage between the WE and RE constants. The negative feedback loop tracks the reference voltage of the RE with an input voltage of the WE. The proposed potentiostat readout circuit is designed in the standard 0.18 µm CMOS process, and the simulated current consumption is 48.54 μA with a 1.8 V power supply. The simulated input-referred noise level was 8.53 pArms. |
| first_indexed | 2024-03-09T18:29:57Z |
| format | Article |
| id | doaj.art-0ff597bae51d4fc3a98364348674ff9d |
| institution | Directory Open Access Journal |
| issn | 2076-3417 |
| language | English |
| last_indexed | 2024-03-09T18:29:57Z |
| publishDate | 2022-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Applied Sciences |
| spelling | doaj.art-0ff597bae51d4fc3a98364348674ff9d2023-11-24T07:33:37ZengMDPI AGApplied Sciences2076-34172022-11-0112221133410.3390/app122211334Low-Noise Potentiostat Readout Circuit with a Chopper Fully Differential Difference Amplifier for Glucose MonitoringGyuri Choi0Kyeongsik Nam1Mookyoung Yoo2Sanggyun Kang3Byeongkwan Jin4Kyounghwan Kim5Hyeoktae Son6Hyoungho Ko7Department of Electronics Engineering, Chungnam National University, Daejeon 34134, KoreaDepartment of Electronics Engineering, Chungnam National University, Daejeon 34134, KoreaDepartment of Electronics Engineering, Chungnam National University, Daejeon 34134, KoreaDepartment of Electronics Engineering, Chungnam National University, Daejeon 34134, KoreaDepartment of Electronics Engineering, Chungnam National University, Daejeon 34134, KoreaDepartment of Electronics Engineering, Chungnam National University, Daejeon 34134, KoreaDepartment of Electronics Engineering, Chungnam National University, Daejeon 34134, KoreaDepartment of Electronics Engineering, Chungnam National University, Daejeon 34134, KoreaThis paper presents a low-noise potentiostat readout circuit with a chopper fully differential difference amplifier (FDDA) for glucose monitoring. Glucose monitoring is necessary for the early diagnosis of diabetes complications and for health management. Ammeter electrochemical sensors are widely used for glucose detection, and in general, a three-electrode structure of a reference electrode (RE), a counter electrode (CE), and a working electrode (WE) is implemented with a potentiostat structure. A low-noise characteristic of the readout circuit is essential for highly accurate glucose monitoring. The chopping technique can reduce low-frequency noises such as 1/f noise and can achieve the required low-noise characteristic. The proposed potentiostat readout circuit is based on a low-noise chopper FDDA with a class-AB output stage. The implementation of the chopper FDDA scheme of the potentiostat readout circuit can decrease the number of amplifiers in the control part of the potentiostat, with reduced power consumption and a wide dynamic output range. The negative feedback loop of the inverting amplifier scheme with the FDDA maintains the voltage between the WE and RE constants. The negative feedback loop tracks the reference voltage of the RE with an input voltage of the WE. The proposed potentiostat readout circuit is designed in the standard 0.18 µm CMOS process, and the simulated current consumption is 48.54 μA with a 1.8 V power supply. The simulated input-referred noise level was 8.53 pArms.https://www.mdpi.com/2076-3417/12/22/11334potentiostat readout circuitglucose monitoringchopper amplifierfully differential difference amplifier |
| spellingShingle | Gyuri Choi Kyeongsik Nam Mookyoung Yoo Sanggyun Kang Byeongkwan Jin Kyounghwan Kim Hyeoktae Son Hyoungho Ko Low-Noise Potentiostat Readout Circuit with a Chopper Fully Differential Difference Amplifier for Glucose Monitoring Applied Sciences potentiostat readout circuit glucose monitoring chopper amplifier fully differential difference amplifier |
| title | Low-Noise Potentiostat Readout Circuit with a Chopper Fully Differential Difference Amplifier for Glucose Monitoring |
| title_full | Low-Noise Potentiostat Readout Circuit with a Chopper Fully Differential Difference Amplifier for Glucose Monitoring |
| title_fullStr | Low-Noise Potentiostat Readout Circuit with a Chopper Fully Differential Difference Amplifier for Glucose Monitoring |
| title_full_unstemmed | Low-Noise Potentiostat Readout Circuit with a Chopper Fully Differential Difference Amplifier for Glucose Monitoring |
| title_short | Low-Noise Potentiostat Readout Circuit with a Chopper Fully Differential Difference Amplifier for Glucose Monitoring |
| title_sort | low noise potentiostat readout circuit with a chopper fully differential difference amplifier for glucose monitoring |
| topic | potentiostat readout circuit glucose monitoring chopper amplifier fully differential difference amplifier |
| url | https://www.mdpi.com/2076-3417/12/22/11334 |
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