ANTIARRHYTMIC EFFICACY OF SOTALOL IN PATIENTS WITH TACHY-BRADY SYNDROME HAVING ATRIAL PACEMAKER WITH DIFFERENT ATRIAL ELECTRODE POSITION

Aim. To evaluate efficacy of the combined therapy (sotalol and constant electric cardiostimulation in AAI regimen) at two atrial electrode position: in low back part of interatrial septum (IAS) and in right atrial auricle (RAA).Material and methods. 20 patients with tachy-brady syndrome were examine...

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Main Author: T. N. Novikova
Format: Article
Language:English
Published: Столичная издательская компания 2016-01-01
Series:Рациональная фармакотерапия в кардиологии
Subjects:
Online Access:https://www.rpcardio.online/jour/article/view/677
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author T. N. Novikova
author_facet T. N. Novikova
author_sort T. N. Novikova
collection DOAJ
description Aim. To evaluate efficacy of the combined therapy (sotalol and constant electric cardiostimulation in AAI regimen) at two atrial electrode position: in low back part of interatrial septum (IAS) and in right atrial auricle (RAA).Material and methods. 20 patients with tachy-brady syndrome were examined. They were randomized in 2 groups depending on atrial electrode position. Sotalol (160 mg daily) was prescribed to all patients in a month after implantation of constant atrial pacemaker (CAP). A number of atrial fibrillation paroxysms (AFP) was evaluated initially, in a month after CAP implantation and in a month after start of sotalol therapy.Results. Significant AFP reduction was observed in IAS stimulation, unlike RAA stimulation. Sotalol addition had essential significance in the termination or reduction of AFP. Sotalol effect did not depend on atrial electrode position.Conclusion. Sotalol usage together with constant electric cardiostimulation significantly reduces AFP irrespectively of atrial electrode position.
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spelling doaj.art-0ffba4f0357e4da895bfad7c3c0149712024-04-01T07:43:28ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532016-01-0154172010.20996/1819-6446-2009-5-4-17-20676ANTIARRHYTMIC EFFICACY OF SOTALOL IN PATIENTS WITH TACHY-BRADY SYNDROME HAVING ATRIAL PACEMAKER WITH DIFFERENT ATRIAL ELECTRODE POSITIONT. N. Novikova0St-Petersburg Medical Academy of Postgraduate Studies, City Pokrovsky HospitalAim. To evaluate efficacy of the combined therapy (sotalol and constant electric cardiostimulation in AAI regimen) at two atrial electrode position: in low back part of interatrial septum (IAS) and in right atrial auricle (RAA).Material and methods. 20 patients with tachy-brady syndrome were examined. They were randomized in 2 groups depending on atrial electrode position. Sotalol (160 mg daily) was prescribed to all patients in a month after implantation of constant atrial pacemaker (CAP). A number of atrial fibrillation paroxysms (AFP) was evaluated initially, in a month after CAP implantation and in a month after start of sotalol therapy.Results. Significant AFP reduction was observed in IAS stimulation, unlike RAA stimulation. Sotalol addition had essential significance in the termination or reduction of AFP. Sotalol effect did not depend on atrial electrode position.Conclusion. Sotalol usage together with constant electric cardiostimulation significantly reduces AFP irrespectively of atrial electrode position.https://www.rpcardio.online/jour/article/view/677atrial fibrillationconstant electric cardiostimulationcombined therapysotalol
spellingShingle T. N. Novikova
ANTIARRHYTMIC EFFICACY OF SOTALOL IN PATIENTS WITH TACHY-BRADY SYNDROME HAVING ATRIAL PACEMAKER WITH DIFFERENT ATRIAL ELECTRODE POSITION
Рациональная фармакотерапия в кардиологии
atrial fibrillation
constant electric cardiostimulation
combined therapy
sotalol
title ANTIARRHYTMIC EFFICACY OF SOTALOL IN PATIENTS WITH TACHY-BRADY SYNDROME HAVING ATRIAL PACEMAKER WITH DIFFERENT ATRIAL ELECTRODE POSITION
title_full ANTIARRHYTMIC EFFICACY OF SOTALOL IN PATIENTS WITH TACHY-BRADY SYNDROME HAVING ATRIAL PACEMAKER WITH DIFFERENT ATRIAL ELECTRODE POSITION
title_fullStr ANTIARRHYTMIC EFFICACY OF SOTALOL IN PATIENTS WITH TACHY-BRADY SYNDROME HAVING ATRIAL PACEMAKER WITH DIFFERENT ATRIAL ELECTRODE POSITION
title_full_unstemmed ANTIARRHYTMIC EFFICACY OF SOTALOL IN PATIENTS WITH TACHY-BRADY SYNDROME HAVING ATRIAL PACEMAKER WITH DIFFERENT ATRIAL ELECTRODE POSITION
title_short ANTIARRHYTMIC EFFICACY OF SOTALOL IN PATIENTS WITH TACHY-BRADY SYNDROME HAVING ATRIAL PACEMAKER WITH DIFFERENT ATRIAL ELECTRODE POSITION
title_sort antiarrhytmic efficacy of sotalol in patients with tachy brady syndrome having atrial pacemaker with different atrial electrode position
topic atrial fibrillation
constant electric cardiostimulation
combined therapy
sotalol
url https://www.rpcardio.online/jour/article/view/677
work_keys_str_mv AT tnnovikova antiarrhytmicefficacyofsotalolinpatientswithtachybradysyndromehavingatrialpacemakerwithdifferentatrialelectrodeposition