Temporal transcription factors determine circuit membership by permanently altering motor neuron-to-muscle synaptic partnerships

How circuit wiring is specified is a key question in developmental neurobiology. Previously, using the Drosophila motor system as a model, we found the classic temporal transcription factor Hunchback acts in NB7-1 neuronal stem cells to control the number of NB7-1 neuronal progeny form functional sy...

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Bibliographic Details
Main Authors: Julia L Meng, Yupu Wang, Robert A Carrillo, Ellie S Heckscher
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-05-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/56898