Comparing Mean Platelet Volume Values in Patients with Recurrent Aphthous Stomatitis and Patients with Behcet’s Disease
Objective:Platelets play an important role in the pathogenesis of disorders associated with the local or systemic inflammation. Mean platelet volume (MPV) is a marker for platelet activation, and larger platelets are more activated. In this study, we aimed to investigate MPV values in patients with...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Galenos Publishing House
2018-07-01
|
| Series: | Bezmiâlem Science |
| Subjects: | |
| Online Access: |
http://bezmialemscience.org/archives/archive-detail/article-preview/comparing-mean-platelet-volume-values-in-patients-/20142
|
| _version_ | 1828014951884652544 |
|---|---|
| author | Dilek BIYIK ÖZKAYA Özlem Su KÜÇÜK Nahide ONSUN |
| author_facet | Dilek BIYIK ÖZKAYA Özlem Su KÜÇÜK Nahide ONSUN |
| author_sort | Dilek BIYIK ÖZKAYA |
| collection | DOAJ |
| description | Objective:Platelets play an important role in the pathogenesis of disorders associated with the local or systemic inflammation. Mean platelet volume (MPV) is a marker for platelet activation, and larger platelets are more activated. In this study, we aimed to investigate MPV values in patients with Behcet’s disease, patients with recurrent aphthous stomatitis, and controls.Methods:Patients with Behcet’s disease and patients with recurrent aphthous stomatitis who presented to a dermatology outpatients clinic were enrolled in this study. Age, sex, MPV values, vitamin B12, and TSH were retrospectively recorded.Results:A total of 113 patients with recurrent aphthous stomatitis, 87 patients with Behcet’s disease, and 71 healthy controls were enrolled in this study. Among them, 74 (65.5%) of the patients with recurrent aphthous stomatitis were females, and 39 (35.5%) were males. Additionally, 50 (63.4%) of the patients with Behcet’s disease were females, and 37 (42.5%) were males. Finally, 45 (63.4%) of the controls were females, and 26 (36.6%) were males. There was no statistically significant difference in MPV values in patients with Behcet’s disease, patients with recurrent aphthous stomatitis, and control group.Conclusion:MPV is a simple and useful parameter seen in routine complete blood count (CBC) laboratory tests. It is investigated as an inflammation marker. Although in some studies, MPV was high in patients with Behcet’s disease, in our study, we did not observe any statistically significant difference in patients with Behcet’s disease, patients with recurrent aphthous stomatitis, and control group. |
| first_indexed | 2024-04-10T10:09:41Z |
| format | Article |
| id | doaj.art-1005f9d5e051473994f701f034e11918 |
| institution | Directory Open Access Journal |
| issn | 2148-2373 2148-2373 |
| language | English |
| last_indexed | 2024-04-10T10:09:41Z |
| publishDate | 2018-07-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Bezmiâlem Science |
| spelling | doaj.art-1005f9d5e051473994f701f034e119182023-02-15T16:22:15ZengGalenos Publishing HouseBezmiâlem Science2148-23732148-23732018-07-016319619910.14235/bs.2018.158713049054Comparing Mean Platelet Volume Values in Patients with Recurrent Aphthous Stomatitis and Patients with Behcet’s DiseaseDilek BIYIK ÖZKAYA0Özlem Su KÜÇÜK1Nahide ONSUN2 Bezmialem Vakıf Üniversitesi Tıp Fakültesi, Deri ve Zührevi Hastalıkları Anabilim Dalı, İstanbul, Türkiye Bezmialem Vakıf Üniversitesi Tıp Fakültesi, Deri ve Zührevi Hastalıkları Anabilim Dalı, İstanbul, Türkiye Bezmialem Vakıf Üniversitesi Tıp Fakültesi, Deri ve Zührevi Hastalıkları Anabilim Dalı, İstanbul, Türkiye Objective:Platelets play an important role in the pathogenesis of disorders associated with the local or systemic inflammation. Mean platelet volume (MPV) is a marker for platelet activation, and larger platelets are more activated. In this study, we aimed to investigate MPV values in patients with Behcet’s disease, patients with recurrent aphthous stomatitis, and controls.Methods:Patients with Behcet’s disease and patients with recurrent aphthous stomatitis who presented to a dermatology outpatients clinic were enrolled in this study. Age, sex, MPV values, vitamin B12, and TSH were retrospectively recorded.Results:A total of 113 patients with recurrent aphthous stomatitis, 87 patients with Behcet’s disease, and 71 healthy controls were enrolled in this study. Among them, 74 (65.5%) of the patients with recurrent aphthous stomatitis were females, and 39 (35.5%) were males. Additionally, 50 (63.4%) of the patients with Behcet’s disease were females, and 37 (42.5%) were males. Finally, 45 (63.4%) of the controls were females, and 26 (36.6%) were males. There was no statistically significant difference in MPV values in patients with Behcet’s disease, patients with recurrent aphthous stomatitis, and control group.Conclusion:MPV is a simple and useful parameter seen in routine complete blood count (CBC) laboratory tests. It is investigated as an inflammation marker. Although in some studies, MPV was high in patients with Behcet’s disease, in our study, we did not observe any statistically significant difference in patients with Behcet’s disease, patients with recurrent aphthous stomatitis, and control group. http://bezmialemscience.org/archives/archive-detail/article-preview/comparing-mean-platelet-volume-values-in-patients-/20142 MPVrecurrent aphthous stomatitisBehcet’s disease |
| spellingShingle | Dilek BIYIK ÖZKAYA Özlem Su KÜÇÜK Nahide ONSUN Comparing Mean Platelet Volume Values in Patients with Recurrent Aphthous Stomatitis and Patients with Behcet’s Disease Bezmiâlem Science MPV recurrent aphthous stomatitis Behcet’s disease |
| title | Comparing Mean Platelet Volume Values in Patients with Recurrent Aphthous Stomatitis and Patients with Behcet’s Disease |
| title_full | Comparing Mean Platelet Volume Values in Patients with Recurrent Aphthous Stomatitis and Patients with Behcet’s Disease |
| title_fullStr | Comparing Mean Platelet Volume Values in Patients with Recurrent Aphthous Stomatitis and Patients with Behcet’s Disease |
| title_full_unstemmed | Comparing Mean Platelet Volume Values in Patients with Recurrent Aphthous Stomatitis and Patients with Behcet’s Disease |
| title_short | Comparing Mean Platelet Volume Values in Patients with Recurrent Aphthous Stomatitis and Patients with Behcet’s Disease |
| title_sort | comparing mean platelet volume values in patients with recurrent aphthous stomatitis and patients with behcet s disease |
| topic | MPV recurrent aphthous stomatitis Behcet’s disease |
| url |
http://bezmialemscience.org/archives/archive-detail/article-preview/comparing-mean-platelet-volume-values-in-patients-/20142
|
| work_keys_str_mv | AT dilekbiyikozkaya comparingmeanplateletvolumevaluesinpatientswithrecurrentaphthousstomatitisandpatientswithbehcetsdisease AT ozlemsukucuk comparingmeanplateletvolumevaluesinpatientswithrecurrentaphthousstomatitisandpatientswithbehcetsdisease AT nahideonsun comparingmeanplateletvolumevaluesinpatientswithrecurrentaphthousstomatitisandpatientswithbehcetsdisease |