Mesenchymal stem cell-based therapy for autoimmune-related fibrotic skin diseases—systemic sclerosis and sclerodermatous graft-versus-host disease

Mesenchymal stem cell-based therapy for autoimmune-related fibrotic skin diseases—systemic sclerosis and sclerodermatous graft-versus-host disease

Abstract Background Systemic sclerosis (SSc) and sclerodermatous graft-versus-host disease (Scl-GVHD)—characterized by similar developmental fibrosis, vascular abnormalities, and innate and adaptive immune response, resulting in severe skin fibrosis at the late stage—are chronic autoimmune diseases...

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Bibliographic Details
Main Authors: Han Yang, Sousan Cheong, Yunfan He, Feng Lu
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Stem Cell Research & Therapy
Subjects:
Mesenchymal stem cells
Autoimmune-related fibrotic skin diseases
Systemic sclerosis
Sclerodermatous graft-versus-host disease
Chronic graft-versus-host disease
MSC-based therapy
Online Access:https://doi.org/10.1186/s13287-023-03543-w

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