Cornus mas (Linnaeus) Novel Devised Medicinal Preparations: Bactericidal Effect against Staphylococcus aureus and Pseudomonas aeruginosa
The medicinal properties of Cornus mas L. (=Cornus mascula L.), Cornaceae, are well described in Hippocratian documents, and recent research provides experimental evidence for some of these properties. However, the chemical components of Cornus mas L. that may be of pharmaceutical importance are rel...
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| Format: | Article |
| Language: | English |
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MDPI AG
2015-06-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/20/6/11202 |
| _version_ | 1818201979923464192 |
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| author | Anthony M. Kyriakopoulos Biswanath Dinda |
| author_facet | Anthony M. Kyriakopoulos Biswanath Dinda |
| author_sort | Anthony M. Kyriakopoulos |
| collection | DOAJ |
| description | The medicinal properties of Cornus mas L. (=Cornus mascula L.), Cornaceae, are well described in Hippocratian documents, and recent research provides experimental evidence for some of these properties. However, the chemical components of Cornus mas L. that may be of pharmaceutical importance are relatively unstable. In this respect a novel methodology for plant nutrient element extraction that provides favorable conditions for simultaneous stabilization of such fragile and unstable structures has been devised. Using this methodology, medicinal preparations derived from Cornus mas L. fresh fruits, proved to possess significant antimicrobial activity selective against S. aureus and P. aeruginosa. This effect became apparent with the addition of sodium bromide in the extraction procedure and varied with the ion availability during extraction. The identification of novel agents with potent antimicrobial activity against these species is of medical importance to overcome the problem of universal antibiotic resistance. |
| first_indexed | 2024-12-12T03:02:10Z |
| format | Article |
| id | doaj.art-1008b130e328434eac137045da452d64 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-12T03:02:10Z |
| publishDate | 2015-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-1008b130e328434eac137045da452d642022-12-22T00:40:36ZengMDPI AGMolecules1420-30492015-06-01206112021121810.3390/molecules200611202molecules200611202Cornus mas (Linnaeus) Novel Devised Medicinal Preparations: Bactericidal Effect against Staphylococcus aureus and Pseudomonas aeruginosaAnthony M. Kyriakopoulos0Biswanath Dinda1Nasco AD Biotechnology Laboratory, 11 Sachtouri Street, 18536 Pireus, GreeceDepartment of Chemistry, Tripura University, Suryamaninagar 799 022 Tripura, IndiaThe medicinal properties of Cornus mas L. (=Cornus mascula L.), Cornaceae, are well described in Hippocratian documents, and recent research provides experimental evidence for some of these properties. However, the chemical components of Cornus mas L. that may be of pharmaceutical importance are relatively unstable. In this respect a novel methodology for plant nutrient element extraction that provides favorable conditions for simultaneous stabilization of such fragile and unstable structures has been devised. Using this methodology, medicinal preparations derived from Cornus mas L. fresh fruits, proved to possess significant antimicrobial activity selective against S. aureus and P. aeruginosa. This effect became apparent with the addition of sodium bromide in the extraction procedure and varied with the ion availability during extraction. The identification of novel agents with potent antimicrobial activity against these species is of medical importance to overcome the problem of universal antibiotic resistance.http://www.mdpi.com/1420-3049/20/6/11202Cornus mas (L.) fresh fruitsnovel medicinal preparationsselective bactericidal effectPseudomonas aeruginosaStaphylococcus aureus |
| spellingShingle | Anthony M. Kyriakopoulos Biswanath Dinda Cornus mas (Linnaeus) Novel Devised Medicinal Preparations: Bactericidal Effect against Staphylococcus aureus and Pseudomonas aeruginosa Molecules Cornus mas (L.) fresh fruits novel medicinal preparations selective bactericidal effect Pseudomonas aeruginosa Staphylococcus aureus |
| title | Cornus mas (Linnaeus) Novel Devised Medicinal Preparations: Bactericidal Effect against Staphylococcus aureus and Pseudomonas aeruginosa |
| title_full | Cornus mas (Linnaeus) Novel Devised Medicinal Preparations: Bactericidal Effect against Staphylococcus aureus and Pseudomonas aeruginosa |
| title_fullStr | Cornus mas (Linnaeus) Novel Devised Medicinal Preparations: Bactericidal Effect against Staphylococcus aureus and Pseudomonas aeruginosa |
| title_full_unstemmed | Cornus mas (Linnaeus) Novel Devised Medicinal Preparations: Bactericidal Effect against Staphylococcus aureus and Pseudomonas aeruginosa |
| title_short | Cornus mas (Linnaeus) Novel Devised Medicinal Preparations: Bactericidal Effect against Staphylococcus aureus and Pseudomonas aeruginosa |
| title_sort | cornus mas linnaeus novel devised medicinal preparations bactericidal effect against staphylococcus aureus and pseudomonas aeruginosa |
| topic | Cornus mas (L.) fresh fruits novel medicinal preparations selective bactericidal effect Pseudomonas aeruginosa Staphylococcus aureus |
| url | http://www.mdpi.com/1420-3049/20/6/11202 |
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