Current role of tribological tests: Striving for full characterization of medicinal and cosmetic products
Tribology investigates the events that happen on the surfaces of two substances/objects that are in direct or indirect contact through assessing friction, lubrication and/or wear. In particular, friction measurements could provide the information on the textural characteristics of (per)oral pharmace...
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Format: | Article |
Language: | srp |
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Pharmaceutical Association of Serbia, Belgrade, Serbia
2023-01-01
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Series: | Arhiv za farmaciju |
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Online Access: | https://scindeks-clanci.ceon.rs/data/pdf/0004-1963/2023/0004-19632302126T.pdf |
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author | Tošić Anđela Stanković Tijana Ilić Tanja Savić Snežana Pantelić Ivana |
author_facet | Tošić Anđela Stanković Tijana Ilić Tanja Savić Snežana Pantelić Ivana |
author_sort | Tošić Anđela |
collection | DOAJ |
description | Tribology investigates the events that happen on the surfaces of two substances/objects that are in direct or indirect contact through assessing friction, lubrication and/or wear. In particular, friction measurements could provide the information on the textural characteristics of (per)oral pharmaceutical preparations and contribute to the understanding of palatability. On the other hand, tribological tests have been more intensively used to characterize topical preparations (pharmaceutical, cosmetic), giving a thorough insight into the tactile and texture properties of these preparations. However, these tests are often combined with rheological, textural, and certain biophysical approaches. Additionally, the materials used for constructing artificial joints and articular cartilages are true tribological systems, developed and optimized in order to have properties that resemble the natural ones. Since tribological studies can be used to assess a wide range of drug dosage forms and products in general, the equipment used may be quite diverse. Accordingly, a special section of this work is committed to the description of the testing equipment's specifications and the applied protocols. The investigation of recently regulatory discovered phenomena, such as transformation/metamorphosis of the vehicle/base of topical preparations, have brought tribology back into focus as a potential assessment method. |
first_indexed | 2024-03-13T06:01:51Z |
format | Article |
id | doaj.art-100bd007a32b4175802a456240d31740 |
institution | Directory Open Access Journal |
issn | 0004-1963 2217-8767 |
language | srp |
last_indexed | 2024-03-13T06:01:51Z |
publishDate | 2023-01-01 |
publisher | Pharmaceutical Association of Serbia, Belgrade, Serbia |
record_format | Article |
series | Arhiv za farmaciju |
spelling | doaj.art-100bd007a32b4175802a456240d317402023-06-12T11:18:04ZsrpPharmaceutical Association of Serbia, Belgrade, SerbiaArhiv za farmaciju0004-19632217-87672023-01-017321261450004-19632302126TCurrent role of tribological tests: Striving for full characterization of medicinal and cosmetic productsTošić Anđela0Stanković Tijana1Ilić Tanja2https://orcid.org/0000-0002-1937-1704Savić Snežana3https://orcid.org/0000-0002-6236-9730Pantelić Ivana4https://orcid.org/0000-0001-6164-4457University of Belgrade, Faculty of Pharmacy, Department of Pharmaceutical Technology and Cosmetology, Belgrade, SerbiaUniversity of Belgrade, Faculty of Pharmacy, Department of Pharmaceutical Technology and Cosmetology, Belgrade, SerbiaUniversity of Belgrade, Faculty of Pharmacy, Department of Pharmaceutical Technology and Cosmetology, Belgrade, SerbiaUniversity of Belgrade, Faculty of Pharmacy, Department of Pharmaceutical Technology and Cosmetology, Belgrade, SerbiaUniversity of Belgrade, Faculty of Pharmacy, Department of Pharmaceutical Technology and Cosmetology, Belgrade, SerbiaTribology investigates the events that happen on the surfaces of two substances/objects that are in direct or indirect contact through assessing friction, lubrication and/or wear. In particular, friction measurements could provide the information on the textural characteristics of (per)oral pharmaceutical preparations and contribute to the understanding of palatability. On the other hand, tribological tests have been more intensively used to characterize topical preparations (pharmaceutical, cosmetic), giving a thorough insight into the tactile and texture properties of these preparations. However, these tests are often combined with rheological, textural, and certain biophysical approaches. Additionally, the materials used for constructing artificial joints and articular cartilages are true tribological systems, developed and optimized in order to have properties that resemble the natural ones. Since tribological studies can be used to assess a wide range of drug dosage forms and products in general, the equipment used may be quite diverse. Accordingly, a special section of this work is committed to the description of the testing equipment's specifications and the applied protocols. The investigation of recently regulatory discovered phenomena, such as transformation/metamorphosis of the vehicle/base of topical preparations, have brought tribology back into focus as a potential assessment method.https://scindeks-clanci.ceon.rs/data/pdf/0004-1963/2023/0004-19632302126T.pdffrictionoral dosage formstopical drugscosmetic productsartificial joint/cartilage |
spellingShingle | Tošić Anđela Stanković Tijana Ilić Tanja Savić Snežana Pantelić Ivana Current role of tribological tests: Striving for full characterization of medicinal and cosmetic products Arhiv za farmaciju friction oral dosage forms topical drugs cosmetic products artificial joint/cartilage |
title | Current role of tribological tests: Striving for full characterization of medicinal and cosmetic products |
title_full | Current role of tribological tests: Striving for full characterization of medicinal and cosmetic products |
title_fullStr | Current role of tribological tests: Striving for full characterization of medicinal and cosmetic products |
title_full_unstemmed | Current role of tribological tests: Striving for full characterization of medicinal and cosmetic products |
title_short | Current role of tribological tests: Striving for full characterization of medicinal and cosmetic products |
title_sort | current role of tribological tests striving for full characterization of medicinal and cosmetic products |
topic | friction oral dosage forms topical drugs cosmetic products artificial joint/cartilage |
url | https://scindeks-clanci.ceon.rs/data/pdf/0004-1963/2023/0004-19632302126T.pdf |
work_keys_str_mv | AT tosicanđela currentroleoftribologicaltestsstrivingforfullcharacterizationofmedicinalandcosmeticproducts AT stankovictijana currentroleoftribologicaltestsstrivingforfullcharacterizationofmedicinalandcosmeticproducts AT ilictanja currentroleoftribologicaltestsstrivingforfullcharacterizationofmedicinalandcosmeticproducts AT savicsnezana currentroleoftribologicaltestsstrivingforfullcharacterizationofmedicinalandcosmeticproducts AT pantelicivana currentroleoftribologicaltestsstrivingforfullcharacterizationofmedicinalandcosmeticproducts |