Current role of tribological tests: Striving for full characterization of medicinal and cosmetic products

Tribology investigates the events that happen on the surfaces of two substances/objects that are in direct or indirect contact through assessing friction, lubrication and/or wear. In particular, friction measurements could provide the information on the textural characteristics of (per)oral pharmace...

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Main Authors: Tošić Anđela, Stanković Tijana, Ilić Tanja, Savić Snežana, Pantelić Ivana
Format: Article
Language:srp
Published: Pharmaceutical Association of Serbia, Belgrade, Serbia 2023-01-01
Series:Arhiv za farmaciju
Subjects:
Online Access:https://scindeks-clanci.ceon.rs/data/pdf/0004-1963/2023/0004-19632302126T.pdf
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author Tošić Anđela
Stanković Tijana
Ilić Tanja
Savić Snežana
Pantelić Ivana
author_facet Tošić Anđela
Stanković Tijana
Ilić Tanja
Savić Snežana
Pantelić Ivana
author_sort Tošić Anđela
collection DOAJ
description Tribology investigates the events that happen on the surfaces of two substances/objects that are in direct or indirect contact through assessing friction, lubrication and/or wear. In particular, friction measurements could provide the information on the textural characteristics of (per)oral pharmaceutical preparations and contribute to the understanding of palatability. On the other hand, tribological tests have been more intensively used to characterize topical preparations (pharmaceutical, cosmetic), giving a thorough insight into the tactile and texture properties of these preparations. However, these tests are often combined with rheological, textural, and certain biophysical approaches. Additionally, the materials used for constructing artificial joints and articular cartilages are true tribological systems, developed and optimized in order to have properties that resemble the natural ones. Since tribological studies can be used to assess a wide range of drug dosage forms and products in general, the equipment used may be quite diverse. Accordingly, a special section of this work is committed to the description of the testing equipment's specifications and the applied protocols. The investigation of recently regulatory discovered phenomena, such as transformation/metamorphosis of the vehicle/base of topical preparations, have brought tribology back into focus as a potential assessment method.
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spelling doaj.art-100bd007a32b4175802a456240d317402023-06-12T11:18:04ZsrpPharmaceutical Association of Serbia, Belgrade, SerbiaArhiv za farmaciju0004-19632217-87672023-01-017321261450004-19632302126TCurrent role of tribological tests: Striving for full characterization of medicinal and cosmetic productsTošić Anđela0Stanković Tijana1Ilić Tanja2https://orcid.org/0000-0002-1937-1704Savić Snežana3https://orcid.org/0000-0002-6236-9730Pantelić Ivana4https://orcid.org/0000-0001-6164-4457University of Belgrade, Faculty of Pharmacy, Department of Pharmaceutical Technology and Cosmetology, Belgrade, SerbiaUniversity of Belgrade, Faculty of Pharmacy, Department of Pharmaceutical Technology and Cosmetology, Belgrade, SerbiaUniversity of Belgrade, Faculty of Pharmacy, Department of Pharmaceutical Technology and Cosmetology, Belgrade, SerbiaUniversity of Belgrade, Faculty of Pharmacy, Department of Pharmaceutical Technology and Cosmetology, Belgrade, SerbiaUniversity of Belgrade, Faculty of Pharmacy, Department of Pharmaceutical Technology and Cosmetology, Belgrade, SerbiaTribology investigates the events that happen on the surfaces of two substances/objects that are in direct or indirect contact through assessing friction, lubrication and/or wear. In particular, friction measurements could provide the information on the textural characteristics of (per)oral pharmaceutical preparations and contribute to the understanding of palatability. On the other hand, tribological tests have been more intensively used to characterize topical preparations (pharmaceutical, cosmetic), giving a thorough insight into the tactile and texture properties of these preparations. However, these tests are often combined with rheological, textural, and certain biophysical approaches. Additionally, the materials used for constructing artificial joints and articular cartilages are true tribological systems, developed and optimized in order to have properties that resemble the natural ones. Since tribological studies can be used to assess a wide range of drug dosage forms and products in general, the equipment used may be quite diverse. Accordingly, a special section of this work is committed to the description of the testing equipment's specifications and the applied protocols. The investigation of recently regulatory discovered phenomena, such as transformation/metamorphosis of the vehicle/base of topical preparations, have brought tribology back into focus as a potential assessment method.https://scindeks-clanci.ceon.rs/data/pdf/0004-1963/2023/0004-19632302126T.pdffrictionoral dosage formstopical drugscosmetic productsartificial joint/cartilage
spellingShingle Tošić Anđela
Stanković Tijana
Ilić Tanja
Savić Snežana
Pantelić Ivana
Current role of tribological tests: Striving for full characterization of medicinal and cosmetic products
Arhiv za farmaciju
friction
oral dosage forms
topical drugs
cosmetic products
artificial joint/cartilage
title Current role of tribological tests: Striving for full characterization of medicinal and cosmetic products
title_full Current role of tribological tests: Striving for full characterization of medicinal and cosmetic products
title_fullStr Current role of tribological tests: Striving for full characterization of medicinal and cosmetic products
title_full_unstemmed Current role of tribological tests: Striving for full characterization of medicinal and cosmetic products
title_short Current role of tribological tests: Striving for full characterization of medicinal and cosmetic products
title_sort current role of tribological tests striving for full characterization of medicinal and cosmetic products
topic friction
oral dosage forms
topical drugs
cosmetic products
artificial joint/cartilage
url https://scindeks-clanci.ceon.rs/data/pdf/0004-1963/2023/0004-19632302126T.pdf
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AT stankovictijana currentroleoftribologicaltestsstrivingforfullcharacterizationofmedicinalandcosmeticproducts
AT ilictanja currentroleoftribologicaltestsstrivingforfullcharacterizationofmedicinalandcosmeticproducts
AT savicsnezana currentroleoftribologicaltestsstrivingforfullcharacterizationofmedicinalandcosmeticproducts
AT pantelicivana currentroleoftribologicaltestsstrivingforfullcharacterizationofmedicinalandcosmeticproducts