Brown–McLean syndrome: the role of iridodonesis

Yanin Suwan, Chaiwat Teekhasaenee, Kaevalin Lekhanont, Wasu Supakontanasan Department of Ophthalmology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand Purpose: The aim of this study was to report a case series of Brown–McLean syndrome (BMS).Methods: The...

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Main Authors: Suwan Y, Teekhasaenee C, Lekhanont K, Supakontanasan W
Format: Article
Language:English
Published: Dove Medical Press 2016-04-01
Series:Clinical Ophthalmology
Subjects:
Online Access:https://www.dovepress.com/brownndashmclean-syndrome-the-role-of-iridodonesis-peer-reviewed-article-OPTH
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author Suwan Y
Teekhasaenee C
Lekhanont K
Supakontanasan W
author_facet Suwan Y
Teekhasaenee C
Lekhanont K
Supakontanasan W
author_sort Suwan Y
collection DOAJ
description Yanin Suwan, Chaiwat Teekhasaenee, Kaevalin Lekhanont, Wasu Supakontanasan Department of Ophthalmology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand Purpose: The aim of this study was to report a case series of Brown–McLean syndrome (BMS).Methods: The charts of 28 patients with BMS at Ramathibodi and Rutnin Hospital from 1981 to 2015 were reviewed.Results: BMS is a rare condition with corneal edema involving the peripheral cornea with orange-brown pigment deposition underlying the edematous area. The edema typically starts inferiorly and advances circumferentially to superior cornea. Central cornea remains clear in most patients. We report 28 patients with BMS that occurred either spontaneously or after various intraocular procedures. Ultrasound biomicroscopy was performed to demonstrate the iridocorneal relationship.Conclusion: Iridocorneal relationship from the ultrasound biomicroscopy study in four patients did not support previous hypothesis about the role of iridodonesis impact on corneal endothelium. Patients with BMS can rarely progress to corneal decompensation; however, they should be periodically monitored and made aware of early clinical signs of their complications. Keywords: Brown–McLean syndrome, peripheral corneal edema, marginal corneal edema, corneal decompensation
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spelling doaj.art-100c69070ba848cf80f8f274f70c61eb2022-12-21T20:36:33ZengDove Medical PressClinical Ophthalmology1177-54832016-04-012016Issue 167167726451Brown–McLean syndrome: the role of iridodonesisSuwan YTeekhasaenee CLekhanont KSupakontanasan WYanin Suwan, Chaiwat Teekhasaenee, Kaevalin Lekhanont, Wasu Supakontanasan Department of Ophthalmology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand Purpose: The aim of this study was to report a case series of Brown–McLean syndrome (BMS).Methods: The charts of 28 patients with BMS at Ramathibodi and Rutnin Hospital from 1981 to 2015 were reviewed.Results: BMS is a rare condition with corneal edema involving the peripheral cornea with orange-brown pigment deposition underlying the edematous area. The edema typically starts inferiorly and advances circumferentially to superior cornea. Central cornea remains clear in most patients. We report 28 patients with BMS that occurred either spontaneously or after various intraocular procedures. Ultrasound biomicroscopy was performed to demonstrate the iridocorneal relationship.Conclusion: Iridocorneal relationship from the ultrasound biomicroscopy study in four patients did not support previous hypothesis about the role of iridodonesis impact on corneal endothelium. Patients with BMS can rarely progress to corneal decompensation; however, they should be periodically monitored and made aware of early clinical signs of their complications. Keywords: Brown–McLean syndrome, peripheral corneal edema, marginal corneal edema, corneal decompensationhttps://www.dovepress.com/brownndashmclean-syndrome-the-role-of-iridodonesis-peer-reviewed-article-OPTHBrown McLean syndrome Peripheral corneal edema Marginal corneal edema Corneal decompensation
spellingShingle Suwan Y
Teekhasaenee C
Lekhanont K
Supakontanasan W
Brown–McLean syndrome: the role of iridodonesis
Clinical Ophthalmology
Brown McLean syndrome Peripheral corneal edema Marginal corneal edema Corneal decompensation
title Brown–McLean syndrome: the role of iridodonesis
title_full Brown–McLean syndrome: the role of iridodonesis
title_fullStr Brown–McLean syndrome: the role of iridodonesis
title_full_unstemmed Brown–McLean syndrome: the role of iridodonesis
title_short Brown–McLean syndrome: the role of iridodonesis
title_sort brown ndash mclean syndrome the role of iridodonesis
topic Brown McLean syndrome Peripheral corneal edema Marginal corneal edema Corneal decompensation
url https://www.dovepress.com/brownndashmclean-syndrome-the-role-of-iridodonesis-peer-reviewed-article-OPTH
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