Neural cell integration into 3D bioprinted skeletal muscle constructs accelerates restoration of muscle function
3D bioprinting of skeletal muscle using primary human muscle progenitor cells results in correct muscle architecture, but functional restoration in rodent models is limited. Here the authors include human neural stem cells into bioprinted skeletal muscle and observe improved architecture and functio...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2020-02-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-020-14930-9 |
| _version_ | 1818857982194089984 |
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| author | Ji Hyun Kim Ickhee Kim Young-Joon Seol In Kap Ko James J. Yoo Anthony Atala Sang Jin Lee |
| author_facet | Ji Hyun Kim Ickhee Kim Young-Joon Seol In Kap Ko James J. Yoo Anthony Atala Sang Jin Lee |
| author_sort | Ji Hyun Kim |
| collection | DOAJ |
| description | 3D bioprinting of skeletal muscle using primary human muscle progenitor cells results in correct muscle architecture, but functional restoration in rodent models is limited. Here the authors include human neural stem cells into bioprinted skeletal muscle and observe improved architecture and function in vivo. |
| first_indexed | 2024-12-19T08:49:02Z |
| format | Article |
| id | doaj.art-100df44b6f774e4298073a310e431d95 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-19T08:49:02Z |
| publishDate | 2020-02-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-100df44b6f774e4298073a310e431d952022-12-21T20:28:46ZengNature PortfolioNature Communications2041-17232020-02-0111111210.1038/s41467-020-14930-9Neural cell integration into 3D bioprinted skeletal muscle constructs accelerates restoration of muscle functionJi Hyun Kim0Ickhee Kim1Young-Joon Seol2In Kap Ko3James J. Yoo4Anthony Atala5Sang Jin Lee6Wake Forest Institute for Regenerative Medicine, Wake Forest School of MedicineWake Forest Institute for Regenerative Medicine, Wake Forest School of MedicineWake Forest Institute for Regenerative Medicine, Wake Forest School of MedicineWake Forest Institute for Regenerative Medicine, Wake Forest School of MedicineWake Forest Institute for Regenerative Medicine, Wake Forest School of MedicineWake Forest Institute for Regenerative Medicine, Wake Forest School of MedicineWake Forest Institute for Regenerative Medicine, Wake Forest School of Medicine3D bioprinting of skeletal muscle using primary human muscle progenitor cells results in correct muscle architecture, but functional restoration in rodent models is limited. Here the authors include human neural stem cells into bioprinted skeletal muscle and observe improved architecture and function in vivo.https://doi.org/10.1038/s41467-020-14930-9 |
| spellingShingle | Ji Hyun Kim Ickhee Kim Young-Joon Seol In Kap Ko James J. Yoo Anthony Atala Sang Jin Lee Neural cell integration into 3D bioprinted skeletal muscle constructs accelerates restoration of muscle function Nature Communications |
| title | Neural cell integration into 3D bioprinted skeletal muscle constructs accelerates restoration of muscle function |
| title_full | Neural cell integration into 3D bioprinted skeletal muscle constructs accelerates restoration of muscle function |
| title_fullStr | Neural cell integration into 3D bioprinted skeletal muscle constructs accelerates restoration of muscle function |
| title_full_unstemmed | Neural cell integration into 3D bioprinted skeletal muscle constructs accelerates restoration of muscle function |
| title_short | Neural cell integration into 3D bioprinted skeletal muscle constructs accelerates restoration of muscle function |
| title_sort | neural cell integration into 3d bioprinted skeletal muscle constructs accelerates restoration of muscle function |
| url | https://doi.org/10.1038/s41467-020-14930-9 |
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