Feasibility and Safety of Percutaneous Cardiac Interventions for Congenital and Acquired Heart Defects in Infants ≤1000 g

The transcatheter closure of patent ductus arteriosus (TCPC) has been demonstrated to be feasible even in infants weighing ≤1000 g. However, other percutaneous cardiac interventions (PCI) for such small infants born with congenital heart defects (CHD) or acquired heart defects (AHD) have not been we...

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Main Authors: Ranjit Philip, Jeffrey Towbin, Neil Tailor, Vijaya Joshi, Jason N. Johnson, Ronak Naik, B. Rush Waller, Shyam Sathanandam
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Children
Subjects:
Online Access:https://www.mdpi.com/2227-9067/8/9/826
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author Ranjit Philip
Jeffrey Towbin
Neil Tailor
Vijaya Joshi
Jason N. Johnson
Ronak Naik
B. Rush Waller
Shyam Sathanandam
author_facet Ranjit Philip
Jeffrey Towbin
Neil Tailor
Vijaya Joshi
Jason N. Johnson
Ronak Naik
B. Rush Waller
Shyam Sathanandam
author_sort Ranjit Philip
collection DOAJ
description The transcatheter closure of patent ductus arteriosus (TCPC) has been demonstrated to be feasible even in infants weighing ≤1000 g. However, other percutaneous cardiac interventions (PCI) for such small infants born with congenital heart defects (CHD) or acquired heart defects (AHD) have not been well described. The purpose of this study was to describe the feasibility and safety of PCI in infants ≤1000 g. A retrospective review was conducted between June 2015 and May 2021, looking at 148 consecutive PCIs performed on infants weighing ≤1000 g at the time of the procedure. The procedural success rate was 100%. The major adverse event (AE) rate for TCPC was 3%, while there were no major AEs for other PCI. It is feasible to perform PCIs in infants weighing ≤1000 g with CHD and AHD using currently available technologies.
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spelling doaj.art-1011c273a71a45c1ba71116e9ff3fe352023-11-22T12:30:41ZengMDPI AGChildren2227-90672021-09-018982610.3390/children8090826Feasibility and Safety of Percutaneous Cardiac Interventions for Congenital and Acquired Heart Defects in Infants ≤1000 gRanjit Philip0Jeffrey Towbin1Neil Tailor2Vijaya Joshi3Jason N. Johnson4Ronak Naik5B. Rush Waller6Shyam Sathanandam7Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN 38163, USADepartment of Pediatrics, University of Tennessee Health Science Center, Memphis, TN 38163, USADepartment of Pediatrics, University of Tennessee Health Science Center, Memphis, TN 38163, USADepartment of Pediatrics, University of Tennessee Health Science Center, Memphis, TN 38163, USADepartment of Pediatrics, University of Tennessee Health Science Center, Memphis, TN 38163, USADepartment of Pediatrics, University of Tennessee Health Science Center, Memphis, TN 38163, USADepartment of Pediatrics, University of Tennessee Health Science Center, Memphis, TN 38163, USADepartment of Pediatrics, University of Tennessee Health Science Center, Memphis, TN 38163, USAThe transcatheter closure of patent ductus arteriosus (TCPC) has been demonstrated to be feasible even in infants weighing ≤1000 g. However, other percutaneous cardiac interventions (PCI) for such small infants born with congenital heart defects (CHD) or acquired heart defects (AHD) have not been well described. The purpose of this study was to describe the feasibility and safety of PCI in infants ≤1000 g. A retrospective review was conducted between June 2015 and May 2021, looking at 148 consecutive PCIs performed on infants weighing ≤1000 g at the time of the procedure. The procedural success rate was 100%. The major adverse event (AE) rate for TCPC was 3%, while there were no major AEs for other PCI. It is feasible to perform PCIs in infants weighing ≤1000 g with CHD and AHD using currently available technologies.https://www.mdpi.com/2227-9067/8/9/826prematuritycardiac catheterizationlow birthweightcongenital heart defectsacquired heart defectspulmonary valvuloplasty
spellingShingle Ranjit Philip
Jeffrey Towbin
Neil Tailor
Vijaya Joshi
Jason N. Johnson
Ronak Naik
B. Rush Waller
Shyam Sathanandam
Feasibility and Safety of Percutaneous Cardiac Interventions for Congenital and Acquired Heart Defects in Infants ≤1000 g
Children
prematurity
cardiac catheterization
low birthweight
congenital heart defects
acquired heart defects
pulmonary valvuloplasty
title Feasibility and Safety of Percutaneous Cardiac Interventions for Congenital and Acquired Heart Defects in Infants ≤1000 g
title_full Feasibility and Safety of Percutaneous Cardiac Interventions for Congenital and Acquired Heart Defects in Infants ≤1000 g
title_fullStr Feasibility and Safety of Percutaneous Cardiac Interventions for Congenital and Acquired Heart Defects in Infants ≤1000 g
title_full_unstemmed Feasibility and Safety of Percutaneous Cardiac Interventions for Congenital and Acquired Heart Defects in Infants ≤1000 g
title_short Feasibility and Safety of Percutaneous Cardiac Interventions for Congenital and Acquired Heart Defects in Infants ≤1000 g
title_sort feasibility and safety of percutaneous cardiac interventions for congenital and acquired heart defects in infants ≤1000 g
topic prematurity
cardiac catheterization
low birthweight
congenital heart defects
acquired heart defects
pulmonary valvuloplasty
url https://www.mdpi.com/2227-9067/8/9/826
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