Ribosomal frameshifting used in influenza A virus expression occurs within the sequence UCC_UUU_CGU and is in the +1 direction

Ribosomal frameshifting used in influenza A virus expression occurs within the sequence UCC_UUU_CGU and is in the +1 direction

Programmed ribosomal frameshifting is used in the expression of many virus genes and some cellular genes. In eukaryotic systems, the most well-characterized mechanism involves –1 tandem tRNA slippage on an X_XXY_YYZ motif. By contrast, the mechanisms involved in programmed +1 (or −2) slippage are mo...

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Bibliographic Details
Main Authors: A. E. Firth, B. W. Jagger, H. M. Wise, C. C. Nelson, K. Parsawar, N. M. Wills, S. Napthine, J. K. Taubenberger, P. Digard, J. F. Atkins
Format: Article
Language:English
Published: The Royal Society 2012-01-01
Series:Open Biology
Subjects:
genetic recoding
ribosomal frameshifting
mass spectrometry
influenza virus
pa-x
translation
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.120109

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