Damaged muscle fibers might masquerade as hybrid fibers – a cautionary note on immunophenotyping mouse muscle with mouse monoclonal antibodies

Damaged muscle fibers might masquerade as hybrid fibers – a cautionary note on immunophenotyping mouse muscle with mouse monoclonal antibodies

We report that, labeling mouse muscle tissue, with mouse monoclonal antibodies specific to slow or fast myosin heavy chain (sMyHC and fMyHC, respectively), can lead to artefactual labeling of damaged muscle fibers, as hybrid fibers (sMyHC+ and fMyHC+). We demonstrate that such erroneous immunopheno...

Полное описание

Библиографические подробности
Главные авторы:	Morium Begam, Joseph A. Roche
Формат:	Статья
Язык:	English
Опубликовано:	PAGEPress Publications 2018-07-01
Серии:	European Journal of Histochemistry
Предметы:	Skeletal muscle myosin heavy chains fiber type immunolabeling hybrid muscle fibers muscle fiber damage
Online-ссылка:	https://ejh.it/index.php/ejh/article/view/2896

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