P-115 SUSCEPTIBILITY TO LIVER DAMAGE IN WOMEN DUE TO RISKY ALCOHOL CONSUMPTION.

Introduction and Objectives: Liver damage from alcohol consumption is different between genders, and the susceptibility shown by women is greater than that of men; there are several factors for this difference to exist. We evaluated the complications of cirrhosis due to alcohol in a group of women a...

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Bibliographic Details
Main Authors: José Luis Pérez-Hernández, Ernaldo Morales-Mairena, Andrea Enríquez-Constantino, Daniel Angel Santana Vargas, Fátima Higuera-de la Tijera
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Annals of Hepatology
Online Access:http://www.sciencedirect.com/science/article/pii/S1665268123001035
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Summary:Introduction and Objectives: Liver damage from alcohol consumption is different between genders, and the susceptibility shown by women is greater than that of men; there are several factors for this difference to exist. We evaluated the complications of cirrhosis due to alcohol in a group of women and compared it with a group of men. This study aimed to compare the effect of alcohol consumption and complications between both genders. Materials and Methods: An observational, descriptive, and analytical study compares the pattern of alcohol consumption, the number of grams of alcohol between men and women, and its complications. Results: 222 patients were included; 122 women (55.0%) with 51.7±11.5 years of age, Child-Pugh A=24 (10.8%), B=69 (30.6%) and C=130 (58.6%). The grammage/day of alcohol was Women 175.6.9±131.4 and Men 301.5±106.7. The type of consumption was regular risk M=6.6%; excessive M=45.9% and H=58.0%; intoxication M=11.5% and H=8.0%; binge M=36.1% and H=34.0%. Next, the comparison of medians with the Mann-Whitney U test for MIH by type of consumption with significant differences is described (see table 1) Conclusions: It was found that women develop more liver damage and more complications with lower consumption of grams of alcohol.
ISSN:1665-2681