Translation and validation of the Sindhi version of the general medication adherence scale in patients with chronic diseases

Background: There is no medication adherence scale available in Sindhi language currently. Hence, the Sindhi speaking population will either use a translator or provide their medical history in another language for documentation of medical conditions. This poses a challenge in monitoring and evaluat...

Full description

Bibliographic Details
Main Authors: Md. Ashraful Islam, Wajiha Iffat, Shahlla Imam, Sadia Shakeel, Abdul Rasheed, Atta Abbas Naqvi
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1235032/full
_version_ 1797679273442541568
author Md. Ashraful Islam
Wajiha Iffat
Shahlla Imam
Sadia Shakeel
Abdul Rasheed
Atta Abbas Naqvi
author_facet Md. Ashraful Islam
Wajiha Iffat
Shahlla Imam
Sadia Shakeel
Abdul Rasheed
Atta Abbas Naqvi
author_sort Md. Ashraful Islam
collection DOAJ
description Background: There is no medication adherence scale available in Sindhi language currently. Hence, the Sindhi speaking population will either use a translator or provide their medical history in another language for documentation of medical conditions. This poses a challenge in monitoring and evaluating adherence to medications within this linguistic community.Aim: The aim of this study was to translate and validate the Sindhi version of the General Medication Adherence Scale (GMAS-S) in patients with chronic diseases.Methods: This was a cross-sectional study of 4 months duration and was conducted in out-patient department of a university affiliated hospital in Karachi, Pakistan. All adults with chronic diseases, who were on long-term medications, and able to read and understand Sindhi language were invited. Convenience sampling was employed and a questionnaire consisting of demographic questions and the Sindhi version of GMAS was used. The translation of the scale was carried out. Confirmatory factor analysis (CFA) was conducted, and a structural equation model (SEM) was developed. Fit indices, namely, goodness of fit index (GFI), adjusted goodness of fit index (AGFI), Tucker Lewis index (TLI), comparative fit index (CFI), and root mean square error of approximation (RMSEA) were reported. Reliability was assessed using Cronbach’s alpha (α), intraclass correlation coefficient (ICC), corrected item-to-total correlation (ITC) and item deletion. Data were analysed through IBM SPSS version 23 and IBM AMOS version 25. The study obtained ethical clearance.Results: A total of 150 responses were analysed. The reliability of the Sindhi version of GMAS was (α) = 0.696. The intraclass correlation coefficient (ICC) was reported at 0.696 (95% CI: 0.618–0.763). The values for the fit indices were as follows: χ2/df = 1.84, GFI = 0.918, TLI = 0.920, CFI = 0.942, AGFI = 0.864, and RMSEA = 0.075. All values except AGFI were in the acceptable ranges and indicated good fitness. Most participants (80.7%) appeared non-adherent to their medications.Conclusion: The results of the study demonstrate that the Sindhi version of the GMAS is a valid and reliable scale to measure adherence in Sindhi speaking persons with chronic diseases.
first_indexed 2024-03-11T23:12:08Z
format Article
id doaj.art-10160fa9d5524e13b25de526c75ec935
institution Directory Open Access Journal
issn 1663-9812
language English
last_indexed 2024-03-11T23:12:08Z
publishDate 2023-09-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Pharmacology
spelling doaj.art-10160fa9d5524e13b25de526c75ec9352023-09-21T07:13:07ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122023-09-011410.3389/fphar.2023.12350321235032Translation and validation of the Sindhi version of the general medication adherence scale in patients with chronic diseasesMd. Ashraful Islam0Wajiha Iffat1Shahlla Imam2Sadia Shakeel3Abdul Rasheed4Atta Abbas Naqvi5Department of Pharmacy Practice, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, Dammam, Saudi ArabiaDepartment of Pharmaceutics, Dow College of Pharmacy, Dow University of Health Sciences, Karachi, PakistanDepartment of Pharmacognosy Institute of Pharmaceutical Sciences Jinnah Sindh Medical University Karachi, Karachi, PakistanDepartment of Pharmacy Practice, Dow College of Pharmacy, Dow University of Health Sciences, Karachi, PakistanInstitute of Pharmaceutical Sciences, Jinnah Sindh Medical University Karachi, Karachi, PakistanReading School of Pharmacy, University of Reading, Whiteknights Campus, Reading, United KingdomBackground: There is no medication adherence scale available in Sindhi language currently. Hence, the Sindhi speaking population will either use a translator or provide their medical history in another language for documentation of medical conditions. This poses a challenge in monitoring and evaluating adherence to medications within this linguistic community.Aim: The aim of this study was to translate and validate the Sindhi version of the General Medication Adherence Scale (GMAS-S) in patients with chronic diseases.Methods: This was a cross-sectional study of 4 months duration and was conducted in out-patient department of a university affiliated hospital in Karachi, Pakistan. All adults with chronic diseases, who were on long-term medications, and able to read and understand Sindhi language were invited. Convenience sampling was employed and a questionnaire consisting of demographic questions and the Sindhi version of GMAS was used. The translation of the scale was carried out. Confirmatory factor analysis (CFA) was conducted, and a structural equation model (SEM) was developed. Fit indices, namely, goodness of fit index (GFI), adjusted goodness of fit index (AGFI), Tucker Lewis index (TLI), comparative fit index (CFI), and root mean square error of approximation (RMSEA) were reported. Reliability was assessed using Cronbach’s alpha (α), intraclass correlation coefficient (ICC), corrected item-to-total correlation (ITC) and item deletion. Data were analysed through IBM SPSS version 23 and IBM AMOS version 25. The study obtained ethical clearance.Results: A total of 150 responses were analysed. The reliability of the Sindhi version of GMAS was (α) = 0.696. The intraclass correlation coefficient (ICC) was reported at 0.696 (95% CI: 0.618–0.763). The values for the fit indices were as follows: χ2/df = 1.84, GFI = 0.918, TLI = 0.920, CFI = 0.942, AGFI = 0.864, and RMSEA = 0.075. All values except AGFI were in the acceptable ranges and indicated good fitness. Most participants (80.7%) appeared non-adherent to their medications.Conclusion: The results of the study demonstrate that the Sindhi version of the GMAS is a valid and reliable scale to measure adherence in Sindhi speaking persons with chronic diseases.https://www.frontiersin.org/articles/10.3389/fphar.2023.1235032/fullmedication adherencepatient preferencesquestionnairevalidation studiesSindhiPakistan
spellingShingle Md. Ashraful Islam
Wajiha Iffat
Shahlla Imam
Sadia Shakeel
Abdul Rasheed
Atta Abbas Naqvi
Translation and validation of the Sindhi version of the general medication adherence scale in patients with chronic diseases
Frontiers in Pharmacology
medication adherence
patient preferences
questionnaire
validation studies
Sindhi
Pakistan
title Translation and validation of the Sindhi version of the general medication adherence scale in patients with chronic diseases
title_full Translation and validation of the Sindhi version of the general medication adherence scale in patients with chronic diseases
title_fullStr Translation and validation of the Sindhi version of the general medication adherence scale in patients with chronic diseases
title_full_unstemmed Translation and validation of the Sindhi version of the general medication adherence scale in patients with chronic diseases
title_short Translation and validation of the Sindhi version of the general medication adherence scale in patients with chronic diseases
title_sort translation and validation of the sindhi version of the general medication adherence scale in patients with chronic diseases
topic medication adherence
patient preferences
questionnaire
validation studies
Sindhi
Pakistan
url https://www.frontiersin.org/articles/10.3389/fphar.2023.1235032/full
work_keys_str_mv AT mdashrafulislam translationandvalidationofthesindhiversionofthegeneralmedicationadherencescaleinpatientswithchronicdiseases
AT wajihaiffat translationandvalidationofthesindhiversionofthegeneralmedicationadherencescaleinpatientswithchronicdiseases
AT shahllaimam translationandvalidationofthesindhiversionofthegeneralmedicationadherencescaleinpatientswithchronicdiseases
AT sadiashakeel translationandvalidationofthesindhiversionofthegeneralmedicationadherencescaleinpatientswithchronicdiseases
AT abdulrasheed translationandvalidationofthesindhiversionofthegeneralmedicationadherencescaleinpatientswithchronicdiseases
AT attaabbasnaqvi translationandvalidationofthesindhiversionofthegeneralmedicationadherencescaleinpatientswithchronicdiseases