Construction of a single nucleotide variant score-related gene-based prognostic model in hepatocellular carcinoma: analysis of multi-independent databases and validation in vitro

Construction of a single nucleotide variant score-related gene-based prognostic model in hepatocellular carcinoma: analysis of multi-independent databases and validation in vitro

Abstract Background The accumulation of single nucleotide variants (SNVs) and the emergence of neoantigens can affect tumour proliferation and the immune microenvironment. However, the SNV-related immune microenvironment characteristics and key genes involved in hepatocellular carcinoma (HCC) are st...

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Bibliographic Details
Main Authors: Yu-Jie Xu, Min-Ke He, Shuang Liu, Li-Chang Huang, Xiao-Yun Bu, Anna Kan, Ming Shi
Format: Article
Language:English
Published: BMC 2021-11-01
Series:Cancer Cell International
Subjects:
Hepatocellular carcinoma
Single nucleotide variant
Prognostic model
Immune microenvironment
Online Access:https://doi.org/10.1186/s12935-021-02321-z

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