Preclinical evaluation of Amblyomin-X, a Kunitz-type protease inhibitor with antitumor activity

Preclinical evaluation of Amblyomin-X, a Kunitz-type protease inhibitor with antitumor activity

Amblyomin-X, a Kunitz-type protease inhibitor, is a recombinant protein that selectively induces apoptosis in tumor cells and promotes tumor reduction in vivo in melanoma animal models. Furthermore, Amblyomin-X was able to drastically reduce lung metastasis in a mice orthotopic kidney tumor model. D...

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Bibliographic Details
Main Authors:	Durvanei A. Maria, Sonia Elisabete A.L. Will, Rosemary V. Bosch, Jean G. Souza, Juliana M. Sciani, Mauricio B. Goldfeder, Giuliana G. Rondon, Ana M. Chudzinski-Tavassi
Format:	Article
Language:	English
Published:	Elsevier 2019-01-01
Series:	Toxicology Reports
Online Access:	http://www.sciencedirect.com/science/article/pii/S2214750018305468

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