Large Lobular Capillary Hemangioma Associated with Ingrown Toenail: Histopathological Features and Case Report
Lobular capillary hemangioma (LCH-PG) is a type of pyogenic granuloma characterized by proliferating blood vessels that resemble conventional granulation tissue. Granulation tissue is very often seen in association with ingrown toenails. Despite the close relationship between both entities, LCH-PG s...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-07-01
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| Series: | Dermatopathology |
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| Online Access: | https://www.mdpi.com/2296-3529/9/3/31 |
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| author | Antonio Córdoba-Fernández María Dolores Jiménez-Cristino Victoria Eugenia Córdoba-Jiménez |
| author_facet | Antonio Córdoba-Fernández María Dolores Jiménez-Cristino Victoria Eugenia Córdoba-Jiménez |
| author_sort | Antonio Córdoba-Fernández |
| collection | DOAJ |
| description | Lobular capillary hemangioma (LCH-PG) is a type of pyogenic granuloma characterized by proliferating blood vessels that resemble conventional granulation tissue. Granulation tissue is very often seen in association with ingrown toenails. Despite the close relationship between both entities, LCH-PG shows clinically different behaviors, such as rapid growth and frequent recurrence. Currently, it is unknown exactly how the different etiological factors contribute to the formation of differences between entities. We present a case of a large LCH-PG associated with chronic onychocryptosis in a 26-year-old man. Histopathological features included extensive signs of ulceration, hyperkeratosis, and patchy epidermal acanthosis with the presence of fibrous septa with lobular areas beneath the ulcerative area. The presence of stroma with a marked proliferation of blood vessels with wall thickening and mixed-type inflammatory changes was also characteristic. In advanced stages of onychocryptosis, as presented here, conventional granulation tissue or pyogenic granuloma can be clinically difficult to distinguish from other benign or malignant neoplasms. Histological examination is mandatory, and excisional biopsy can provide a definitive diagnosis. |
| first_indexed | 2024-03-10T00:17:35Z |
| format | Article |
| id | doaj.art-101b1fbc52bd458f92d23d0b4910a76b |
| institution | Directory Open Access Journal |
| issn | 2296-3529 |
| language | English |
| last_indexed | 2024-03-10T00:17:35Z |
| publishDate | 2022-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Dermatopathology |
| spelling | doaj.art-101b1fbc52bd458f92d23d0b4910a76b2023-11-23T15:47:25ZengMDPI AGDermatopathology2296-35292022-07-019327127610.3390/dermatopathology9030031Large Lobular Capillary Hemangioma Associated with Ingrown Toenail: Histopathological Features and Case ReportAntonio Córdoba-Fernández0María Dolores Jiménez-Cristino1Victoria Eugenia Córdoba-Jiménez2Departamento de Podología, Universidad de Sevilla, C/Avicena s/n, 41009 Sevilla, SpainDepartamento de Podología, Universidad de Sevilla, C/Avicena s/n, 41009 Sevilla, SpainPrivate Practice, C/Dr. Fleming 13, Bajo B, Castilleja de la Cuesta, 41950 Sevilla, SpainLobular capillary hemangioma (LCH-PG) is a type of pyogenic granuloma characterized by proliferating blood vessels that resemble conventional granulation tissue. Granulation tissue is very often seen in association with ingrown toenails. Despite the close relationship between both entities, LCH-PG shows clinically different behaviors, such as rapid growth and frequent recurrence. Currently, it is unknown exactly how the different etiological factors contribute to the formation of differences between entities. We present a case of a large LCH-PG associated with chronic onychocryptosis in a 26-year-old man. Histopathological features included extensive signs of ulceration, hyperkeratosis, and patchy epidermal acanthosis with the presence of fibrous septa with lobular areas beneath the ulcerative area. The presence of stroma with a marked proliferation of blood vessels with wall thickening and mixed-type inflammatory changes was also characteristic. In advanced stages of onychocryptosis, as presented here, conventional granulation tissue or pyogenic granuloma can be clinically difficult to distinguish from other benign or malignant neoplasms. Histological examination is mandatory, and excisional biopsy can provide a definitive diagnosis.https://www.mdpi.com/2296-3529/9/3/31capillary hemangiomapiogenic granulomagranulation tissueingrown toenailonychocryptosis |
| spellingShingle | Antonio Córdoba-Fernández María Dolores Jiménez-Cristino Victoria Eugenia Córdoba-Jiménez Large Lobular Capillary Hemangioma Associated with Ingrown Toenail: Histopathological Features and Case Report Dermatopathology capillary hemangioma piogenic granuloma granulation tissue ingrown toenail onychocryptosis |
| title | Large Lobular Capillary Hemangioma Associated with Ingrown Toenail: Histopathological Features and Case Report |
| title_full | Large Lobular Capillary Hemangioma Associated with Ingrown Toenail: Histopathological Features and Case Report |
| title_fullStr | Large Lobular Capillary Hemangioma Associated with Ingrown Toenail: Histopathological Features and Case Report |
| title_full_unstemmed | Large Lobular Capillary Hemangioma Associated with Ingrown Toenail: Histopathological Features and Case Report |
| title_short | Large Lobular Capillary Hemangioma Associated with Ingrown Toenail: Histopathological Features and Case Report |
| title_sort | large lobular capillary hemangioma associated with ingrown toenail histopathological features and case report |
| topic | capillary hemangioma piogenic granuloma granulation tissue ingrown toenail onychocryptosis |
| url | https://www.mdpi.com/2296-3529/9/3/31 |
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