Oxonium Ion Guided Analysis of Quantitative Proteomics Data Reveals Site-Specific <i>O</i>-Glycosylation of Anterior Gradient Protein 2 (AGR2)

Oxonium Ion Guided Analysis of Quantitative Proteomics Data Reveals Site-Specific <i>O</i>-Glycosylation of Anterior Gradient Protein 2 (AGR2)

Developments in mass spectrometry (MS)-based analyses of glycoproteins have been important to study changes in glycosylation related to disease. Recently, the characteristic pattern of oxonium ions in glycopeptide fragmentation spectra had been used to assign different sets of glycopeptides. In part...

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Bibliographic Details
Main Authors: Martina Pirro, Yassene Mohammed, Arnoud H. de Ru, George M. C. Janssen, Rayman T. N. Tjokrodirijo, Katarina Madunić, Manfred Wuhrer, Peter A. van Veelen, Paul J. Hensbergen
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
glycoproteomics
TMT labeling
oxonium ion
LC−MS/MS
<i>O</i>-glycosylation
colorectal cancer
Online Access:https://www.mdpi.com/1422-0067/22/10/5369

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