Effect of Humantenine on mRNA m6A Modification and Expression in Human Colon Cancer Cell Line HCT116

Effect of Humantenine on mRNA m6A Modification and Expression in Human Colon Cancer Cell Line HCT116

Humantenine, an alkaloid isolated from the medicinal herb <i>Gelsemium elegans</i> (Gardner & Chapm.) Benth., has been reported to induce intestinal irritation, but the underlying toxicological mechanisms remain unclear. The object of the present study was to investigate the RNA N6-m...

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Bibliographic Details
Main Authors: Yajiao Wu, Xiaoying Chen, Wenqiang Bao, Xinyu Hong, Chutao Li, Jiatong Lu, Dongcheng Zhang, An Zhu
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Genes
Subjects:
humantenine
m6A modification
transcriptome
tight junction
actin cytoskeleton
Online Access:https://www.mdpi.com/2073-4425/13/5/781

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