Synthesis, characterization, and molecular modeling of novel 1,3,4-oxadiazole derivatives of mefenamic acid

Synthesis, characterization, and molecular modeling of novel 1,3,4-oxadiazole derivatives of mefenamic acid

A novel series of 1,3,4-oxadiazole derivatives of mefenamic acid was obtained by reacting hydrazones of mefenamic acid with anhydrous acetic anhydride. The mefenamic hydrazones were obtained by reacting different substituted aldehydes with mefenamic acid hydrazide. All the compounds were characteriz...

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Bibliographic Details
Main Authors:	Bhat Mashooq A., Naglah Ahmed M., Bakheit Ahmed Hassan, Al-Omar Mohamad A.
Format:	Article
Language:	English
Published:	Sciendo 2024-03-01
Series:	Polish Journal of Chemical Technology
Subjects:	mefenamic acid 1,3,4-oxadiazoles hydrazones molecular docking cox-1/cox-2 enzymes
Online Access:	https://doi.org/10.2478/pjct-2024-0016

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