Knockout of <i>Rlim</i> Results in a Sex Ratio Shift toward Males but Superovulation Cannot Compensate for the Reduced Litter Size

Knockout of <i>Rlim</i> Results in a Sex Ratio Shift toward Males but Superovulation Cannot Compensate for the Reduced Litter Size

Technologies that can preselect offspring gender hold great promise for improving farm animal productivity and preventing human sex-related hereditary diseases. The maternal <i>Rlim</i> allele is required for imprinted X-chromosome inactivation, which is essential for the normal developm...

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Bibliographic Details
Main Authors: Jingfeng Peng, Yunfei Hou, Shici Wu, Zicong Li, Zhenfang Wu
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Animals
Subjects:
sex control
sex ratio
<i>Rlim</i>
X-chromosome inactivation
superovulation
litter size
Online Access:https://www.mdpi.com/2076-2615/13/6/1079

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