HIV-1 envelope subregion length variation during disease progression.

HIV-1 envelope subregion length variation during disease progression.

The V3 loop of the HIV-1 Env protein is the primary determinant of viral coreceptor usage, whereas the V1V2 loop region is thought to influence coreceptor binding and participate in shielding of neutralization-sensitive regions of the Env glycoprotein gp120 from antibody responses. The functional pr...

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Bibliographic Details
Main Authors: Marcel E Curlin, Rafael Zioni, Stephen E Hawes, Yi Liu, Wenjie Deng, Geoffrey S Gottlieb, Tuofu Zhu, James I Mullins
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-12-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3002983?pdf=render

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http://europepmc.org/articles/PMC3002983?pdf=render

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