High-level expression and purification of soluble recombinant FGF21 protein by SUMO fusion in <it>Escherichia coli</it>

High-level expression and purification of soluble recombinant FGF21 protein by SUMO fusion in <it>Escherichia coli</it>

<p>Abstract</p> <p>Background</p> <p>Fibroblast growth factor 21 (FGF21) is a promising drug candidate to combat metabolic diseases. However, high-level expression and purification of recombinant FGF21 (rFGF21) in <it>Escherichia coli (E. coli) </it>is diffi...

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Bibliographic Details
Main Authors:	Huang Yadong, Qin Yuxia, Wan Xiaoshan, Zhang Yaofang, Fu Lianjun, Zhao Hongxin, Xiao Yechen, Wang Huiyan, Gao Hongchang, Li Xiaokun
Format:	Article
Language:	English
Published:	BMC 2010-02-01
Series:	BMC Biotechnology
Online Access:	http://www.biomedcentral.com/1472-6750/10/14

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