Challenges to improved therapeutics for metastatic castrate resistant prostate cancer: from recent successes and failures

<p>Abstract</p> <p>Men with metastatic castration-resistant prostate cancer (mCRPC) carry poor prognosis despite the use of docetaxel-based regimens which has modest survival benefit shown by randomized clinical trials. Significant progress in the discovery of novel therapeutic age...

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Bibliographic Details
Main Authors: Huang Xuan, Chau Cindy H, Figg William D
Format: Article
Language:English
Published: BMC 2012-07-01
Series:Journal of Hematology & Oncology
Online Access:http://www.jhoonline.org/content/5/1/35