Inhibitors of Nucleotide Biosynthesis as Candidates for a Wide Spectrum of Antiviral Chemotherapy
Emerging and re-emerging viruses have been a challenge in public health in recent decades. Host-targeted antivirals (HTA) directed at cellular molecules or pathways involved in virus multiplication represent an interesting strategy to combat viruses presently lacking effective chemotherapy. HTA coul...
Main Authors: | Claudia Soledad Sepúlveda, Cybele Carina García, Elsa Beatriz Damonte |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-08-01
|
Series: | Microorganisms |
Subjects: | |
Online Access: | https://www.mdpi.com/2076-2607/10/8/1631 |
Similar Items
-
Novel Dihydroorotate Dehydrogenase Inhibitors with Potent Interferon-Independent Antiviral Activity against Mammarenaviruses In Vitro
by: Yu-Jin Kim, et al.
Published: (2020-07-01) -
The Novel <i>h</i>DHODH Inhibitor MEDS433 Prevents Influenza Virus Replication by Blocking Pyrimidine Biosynthesis
by: Giulia Sibille, et al.
Published: (2022-10-01) -
Integrative Analyses of Pyrimidine Salvage Pathway-Related Genes Revealing the Associations Between UPP1 and Tumor Microenvironment
by: Li Y, et al.
Published: (2024-01-01) -
Early-Phase Drive to the Precursor Pool: Chloroviruses Dive into the Deep End of Nucleotide Metabolism
by: David D. Dunigan, et al.
Published: (2023-03-01) -
Impaired Nicotinamide Adenine Dinucleotide Biosynthesis in the Kidney of Chronic Kidney Disease
by: Xinhui Liu, et al.
Published: (2021-09-01)