Chemical composition and antifungal activity of essential oil from Eucalyptus smithii against dermatophytes
ABSTRACT INTRODUCTION: In this study, we evaluated the chemical composition of a commercial sample of essential oil from Eucalyptus smithii R.T. Baker and its antifungal activity against Microsporum canis ATCC 32903, Microsporum gypseum ATCC 14683, Trichophyton mentagrophytes ATCC 9533, T. mentagro...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Medicina Tropical (SBMT)
2015-12-01
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| Series: | Revista da Sociedade Brasileira de Medicina Tropical |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822015000600746&lng=en&tlng=en |
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| author | Edilene Bolutari Baptista Danielle Cristina Zimmermann-Franco Alexandre Augusto Barros Lataliza Nádia Rezende Barbosa Raposo |
| author_facet | Edilene Bolutari Baptista Danielle Cristina Zimmermann-Franco Alexandre Augusto Barros Lataliza Nádia Rezende Barbosa Raposo |
| author_sort | Edilene Bolutari Baptista |
| collection | DOAJ |
| description | ABSTRACT INTRODUCTION: In this study, we evaluated the chemical composition of a commercial sample of essential oil from Eucalyptus smithii R.T. Baker and its antifungal activity against Microsporum canis ATCC 32903, Microsporum gypseum ATCC 14683, Trichophyton mentagrophytes ATCC 9533, T. mentagrophytes ATCC 11480, T. mentagrophytes ATCC 11481, and Trichophyton rubrum CCT 5507. METHODS: Morphological changes in these fungi after treatment with the oil were determined by scanning electron microscopy (SEM). The antifungal activity of the oil was determined on the basis of minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) values. RESULTS: The compound 1,8-cineole was found to be the predominant component (72.2%) of the essential oil. The MIC values of the oil ranged from 62.5μg·mL−1 to >1,000μg·mL−1, and the MFC values of the oil ranged from 125μg·mL−1 to >1,000μg·mL−1. SEM analysis showed physical damage and morphological alterations in the fungi exposed to this oil. CONCLUSIONS: We demonstrated the potential of Eucalyptus smithii essential oil as a natural therapeutic agent for the treatment of dermatophytosis. |
| first_indexed | 2024-12-12T19:45:39Z |
| format | Article |
| id | doaj.art-102d8a49ccbf4885af81e2a2ec0094a4 |
| institution | Directory Open Access Journal |
| issn | 1678-9849 |
| language | English |
| last_indexed | 2024-12-12T19:45:39Z |
| publishDate | 2015-12-01 |
| publisher | Sociedade Brasileira de Medicina Tropical (SBMT) |
| record_format | Article |
| series | Revista da Sociedade Brasileira de Medicina Tropical |
| spelling | doaj.art-102d8a49ccbf4885af81e2a2ec0094a42022-12-22T00:14:06ZengSociedade Brasileira de Medicina Tropical (SBMT)Revista da Sociedade Brasileira de Medicina Tropical1678-98492015-12-0148674675210.1590/0037-8682-0188-2015S0037-86822015000600746Chemical composition and antifungal activity of essential oil from Eucalyptus smithii against dermatophytesEdilene Bolutari BaptistaDanielle Cristina Zimmermann-FrancoAlexandre Augusto Barros LatalizaNádia Rezende Barbosa RaposoABSTRACT INTRODUCTION: In this study, we evaluated the chemical composition of a commercial sample of essential oil from Eucalyptus smithii R.T. Baker and its antifungal activity against Microsporum canis ATCC 32903, Microsporum gypseum ATCC 14683, Trichophyton mentagrophytes ATCC 9533, T. mentagrophytes ATCC 11480, T. mentagrophytes ATCC 11481, and Trichophyton rubrum CCT 5507. METHODS: Morphological changes in these fungi after treatment with the oil were determined by scanning electron microscopy (SEM). The antifungal activity of the oil was determined on the basis of minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) values. RESULTS: The compound 1,8-cineole was found to be the predominant component (72.2%) of the essential oil. The MIC values of the oil ranged from 62.5μg·mL−1 to >1,000μg·mL−1, and the MFC values of the oil ranged from 125μg·mL−1 to >1,000μg·mL−1. SEM analysis showed physical damage and morphological alterations in the fungi exposed to this oil. CONCLUSIONS: We demonstrated the potential of Eucalyptus smithii essential oil as a natural therapeutic agent for the treatment of dermatophytosis.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822015000600746&lng=en&tlng=enEucalyptus smithiiDermatophytesMedicinal plantsAntifungal activityEssential oil. |
| spellingShingle | Edilene Bolutari Baptista Danielle Cristina Zimmermann-Franco Alexandre Augusto Barros Lataliza Nádia Rezende Barbosa Raposo Chemical composition and antifungal activity of essential oil from Eucalyptus smithii against dermatophytes Revista da Sociedade Brasileira de Medicina Tropical Eucalyptus smithii Dermatophytes Medicinal plants Antifungal activity Essential oil. |
| title | Chemical composition and antifungal activity of essential oil from Eucalyptus smithii against dermatophytes |
| title_full | Chemical composition and antifungal activity of essential oil from Eucalyptus smithii against dermatophytes |
| title_fullStr | Chemical composition and antifungal activity of essential oil from Eucalyptus smithii against dermatophytes |
| title_full_unstemmed | Chemical composition and antifungal activity of essential oil from Eucalyptus smithii against dermatophytes |
| title_short | Chemical composition and antifungal activity of essential oil from Eucalyptus smithii against dermatophytes |
| title_sort | chemical composition and antifungal activity of essential oil from eucalyptus smithii against dermatophytes |
| topic | Eucalyptus smithii Dermatophytes Medicinal plants Antifungal activity Essential oil. |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822015000600746&lng=en&tlng=en |
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