Comparison between Human Immunodeficiency Virus Positive and Negative Patients with Tuberculosis in Southern Brazil
The objective of this study is to determine the different characteristics of human immunodeficiency virus (HIV) positive and negative patients treated for tuberculosis (TBC) in a tertiary hospital in Southern Brazil. We conducted a retrospective cohort study over a 5-year period, from January 1992 t...
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| Format: | Article |
| Language: | English |
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Fundação Oswaldo Cruz (FIOCRUZ)
1999-05-01
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| Series: | Memorias do Instituto Oswaldo Cruz |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761999000300017 |
| _version_ | 1797718334725160960 |
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| author | Lucélia Henn Fabiano Nagel Felipe Dal Pizzol |
| author_facet | Lucélia Henn Fabiano Nagel Felipe Dal Pizzol |
| author_sort | Lucélia Henn |
| collection | DOAJ |
| description | The objective of this study is to determine the different characteristics of human immunodeficiency virus (HIV) positive and negative patients treated for tuberculosis (TBC) in a tertiary hospital in Southern Brazil. We conducted a retrospective cohort study over a 5-year period, from January 1992 through December 1996. We reviewed medical charts of patients from our institution who received TBC treatment. We reviewed 167 medical charts of patients with confirmed TBC. HIV positivity was detected in 74 patients. There were statistically significant difference between HIV positive and negative patients in sex and age. HIV-infected patients showed significantly more signs of bacteremia than HIV-negative patients. Extra-pulmonary TBC was present respectively in 13 (17.6%) and 21 (22.6%) HIV positive and negative patients. There was a significant difference between chest radiograph presentation in HIV positive and negative patients. There were significantly lower hematocrit, hemoglobin, leukocyte and lymphocyte levels in HIV-positive compared to HIV-negative patients. Outcome was significantly different in the two groups with a death rate of 36.5% and 10.8% in HIV-positive and in HIV-negative patients. The difference between HIV positive and negative patients may have importance in the diagnosis, management and prognosis of patients with TBC. |
| first_indexed | 2024-03-12T08:49:31Z |
| format | Article |
| id | doaj.art-102fac1b27c641fd9272d0b63d125d32 |
| institution | Directory Open Access Journal |
| issn | 0074-0276 1678-8060 |
| language | English |
| last_indexed | 2024-03-12T08:49:31Z |
| publishDate | 1999-05-01 |
| publisher | Fundação Oswaldo Cruz (FIOCRUZ) |
| record_format | Article |
| series | Memorias do Instituto Oswaldo Cruz |
| spelling | doaj.art-102fac1b27c641fd9272d0b63d125d322023-09-02T16:22:02ZengFundação Oswaldo Cruz (FIOCRUZ)Memorias do Instituto Oswaldo Cruz0074-02761678-80601999-05-0194337738110.1590/S0074-02761999000300017Comparison between Human Immunodeficiency Virus Positive and Negative Patients with Tuberculosis in Southern BrazilLucélia HennFabiano NagelFelipe Dal PizzolThe objective of this study is to determine the different characteristics of human immunodeficiency virus (HIV) positive and negative patients treated for tuberculosis (TBC) in a tertiary hospital in Southern Brazil. We conducted a retrospective cohort study over a 5-year period, from January 1992 through December 1996. We reviewed medical charts of patients from our institution who received TBC treatment. We reviewed 167 medical charts of patients with confirmed TBC. HIV positivity was detected in 74 patients. There were statistically significant difference between HIV positive and negative patients in sex and age. HIV-infected patients showed significantly more signs of bacteremia than HIV-negative patients. Extra-pulmonary TBC was present respectively in 13 (17.6%) and 21 (22.6%) HIV positive and negative patients. There was a significant difference between chest radiograph presentation in HIV positive and negative patients. There were significantly lower hematocrit, hemoglobin, leukocyte and lymphocyte levels in HIV-positive compared to HIV-negative patients. Outcome was significantly different in the two groups with a death rate of 36.5% and 10.8% in HIV-positive and in HIV-negative patients. The difference between HIV positive and negative patients may have importance in the diagnosis, management and prognosis of patients with TBC.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761999000300017tuberculosishuman immunodeficiency virus (HIV) infectiondiagnosisprognosisBrazil |
| spellingShingle | Lucélia Henn Fabiano Nagel Felipe Dal Pizzol Comparison between Human Immunodeficiency Virus Positive and Negative Patients with Tuberculosis in Southern Brazil Memorias do Instituto Oswaldo Cruz tuberculosis human immunodeficiency virus (HIV) infection diagnosis prognosis Brazil |
| title | Comparison between Human Immunodeficiency Virus Positive and Negative Patients with Tuberculosis in Southern Brazil |
| title_full | Comparison between Human Immunodeficiency Virus Positive and Negative Patients with Tuberculosis in Southern Brazil |
| title_fullStr | Comparison between Human Immunodeficiency Virus Positive and Negative Patients with Tuberculosis in Southern Brazil |
| title_full_unstemmed | Comparison between Human Immunodeficiency Virus Positive and Negative Patients with Tuberculosis in Southern Brazil |
| title_short | Comparison between Human Immunodeficiency Virus Positive and Negative Patients with Tuberculosis in Southern Brazil |
| title_sort | comparison between human immunodeficiency virus positive and negative patients with tuberculosis in southern brazil |
| topic | tuberculosis human immunodeficiency virus (HIV) infection diagnosis prognosis Brazil |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761999000300017 |
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