A Cytohistopathological Correlation Study of Skin Lesions in Leprosy: An Experience in a Tertiary Care Hospital in South India
Background Leprosy is a granulomatous disease caused by Mycobacterium leprae. Early detection and clinical diagnosis remain a challenge, especially in paucibacillary cases and initial lesions during early phases of leprosy. Use of cytological methods can reduce time for diagnosis, especially in peri...
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| Format: | Article |
| Language: | English |
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2023-07-01
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| Series: | Journal of Laboratory Physicians |
| Subjects: | |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1771020 |
| _version_ | 1797780800812351488 |
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| author | Madana Padma Ramya Katta |
| author_facet | Madana Padma Ramya Katta |
| author_sort | Madana Padma |
| collection | DOAJ |
| description | Background Leprosy is a granulomatous disease caused by Mycobacterium leprae. Early detection and clinical diagnosis remain a challenge, especially in paucibacillary cases and initial lesions during early phases of leprosy. Use of cytological methods can reduce time for diagnosis, especially in peripheral centers.
Objectives The present study was taken up to calculate the correlation between cytology and histopathology of skin lesions in leprosy.
Material & Methods This study is a 2-year retrospective observational study taken up in the Department of Pathology, Rangaraya Medical College and Government General Hospital, Kakinada, Andhra Pradesh. A total of 49 cases of clinically suspected leprosy were included in the study. Skin biopsies and cytological smears were examined in all cases.
Results A total of 49 cases of clinically suspected leprosy were included in the study. The age incidence ranged between 9 and 72 years. There was a male preponderance. The overall diagnostic accuracy of fine-needle aspiration smears was 83.3% and that of slit-skin smears was 62.1%.
Conclusion Cytological examination being a simple, less time-consuming, and easy technique can enhance the diagnostic accuracy in detection of leprosy and act as an adjunct to clinical diagnosis. |
| first_indexed | 2024-03-12T23:48:59Z |
| format | Article |
| id | doaj.art-102fedb840f44ab5a1635a072351feaa |
| institution | Directory Open Access Journal |
| issn | 0974-2727 0974-7826 |
| language | English |
| last_indexed | 2024-03-12T23:48:59Z |
| publishDate | 2023-07-01 |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | Journal of Laboratory Physicians |
| spelling | doaj.art-102fedb840f44ab5a1635a072351feaa2023-07-13T22:48:48ZengThieme Medical and Scientific Publishers Pvt. Ltd.Journal of Laboratory Physicians0974-27270974-78262023-07-0110.1055/s-0043-1771020A Cytohistopathological Correlation Study of Skin Lesions in Leprosy: An Experience in a Tertiary Care Hospital in South IndiaMadana Padma0Ramya Katta1Department of Pathology, Guntur Medical College, Guntur, Andhra Pradesh, IndiaDepartment of Pathology, Guntur Medical College, Guntur, Andhra Pradesh, IndiaBackground Leprosy is a granulomatous disease caused by Mycobacterium leprae. Early detection and clinical diagnosis remain a challenge, especially in paucibacillary cases and initial lesions during early phases of leprosy. Use of cytological methods can reduce time for diagnosis, especially in peripheral centers. Objectives The present study was taken up to calculate the correlation between cytology and histopathology of skin lesions in leprosy. Material & Methods This study is a 2-year retrospective observational study taken up in the Department of Pathology, Rangaraya Medical College and Government General Hospital, Kakinada, Andhra Pradesh. A total of 49 cases of clinically suspected leprosy were included in the study. Skin biopsies and cytological smears were examined in all cases. Results A total of 49 cases of clinically suspected leprosy were included in the study. The age incidence ranged between 9 and 72 years. There was a male preponderance. The overall diagnostic accuracy of fine-needle aspiration smears was 83.3% and that of slit-skin smears was 62.1%. Conclusion Cytological examination being a simple, less time-consuming, and easy technique can enhance the diagnostic accuracy in detection of leprosy and act as an adjunct to clinical diagnosis.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1771020hansen's diseasefite stainzeihl–neelsen stainridley–jopling scale |
| spellingShingle | Madana Padma Ramya Katta A Cytohistopathological Correlation Study of Skin Lesions in Leprosy: An Experience in a Tertiary Care Hospital in South India Journal of Laboratory Physicians hansen's disease fite stain zeihl–neelsen stain ridley–jopling scale |
| title | A Cytohistopathological Correlation Study of Skin Lesions in Leprosy: An Experience in a Tertiary Care Hospital in South India |
| title_full | A Cytohistopathological Correlation Study of Skin Lesions in Leprosy: An Experience in a Tertiary Care Hospital in South India |
| title_fullStr | A Cytohistopathological Correlation Study of Skin Lesions in Leprosy: An Experience in a Tertiary Care Hospital in South India |
| title_full_unstemmed | A Cytohistopathological Correlation Study of Skin Lesions in Leprosy: An Experience in a Tertiary Care Hospital in South India |
| title_short | A Cytohistopathological Correlation Study of Skin Lesions in Leprosy: An Experience in a Tertiary Care Hospital in South India |
| title_sort | cytohistopathological correlation study of skin lesions in leprosy an experience in a tertiary care hospital in south india |
| topic | hansen's disease fite stain zeihl–neelsen stain ridley–jopling scale |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1771020 |
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