Rare Pediatric Cerebellar High-Grade Gliomas Mimic Medulloblastomas Histologically and Transcriptomically and Show p53 Mutations

Rare Pediatric Cerebellar High-Grade Gliomas Mimic Medulloblastomas Histologically and Transcriptomically and Show p53 Mutations

Pediatric high-grade gliomas (HGG) of the cerebellum are rare, and only a few cases have been documented in detail in the literature. A major differential diagnosis for poorly differentiated tumors in the cerebellum in children is medulloblastoma. In this study, we described the histological and mol...

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Bibliographic Details
Main Authors: Zhi-Feng Shi, Kay Ka-Wai Li, Anthony Pak-Yin Liu, Nellie Yuk-Fei Chung, Chit Chow, Hong Chen, Nim-Chi Amanda Kan, Xian-Lun Zhu, Danny Tat-Ming Chan, Ying Mao, Ho-Keung Ng
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Cancers
Subjects:
children
high-grade gliomas
p53
PDGFRA
MYCN
Online Access:https://www.mdpi.com/2072-6694/16/1/232

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