Floret-like multinucleated giant cells in neurofibroma

<p>Abstract</p> <p>This short report discusses a case of neurofibroma containing floret-like multinucleated giant cells. This being the second such case in the literature. Floret-like multinucleated giant cells have been reported in gynaecomastia and neurofibroma in neurofibromatos...

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Main Authors: Golka Dariusz, Shaktawat Sameer
Format: Article
Language:English
Published: BMC 2007-12-01
Series:Diagnostic Pathology
Online Access:http://www.diagnosticpathology.org/content/2/1/47
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author Golka Dariusz
Shaktawat Sameer
author_facet Golka Dariusz
Shaktawat Sameer
author_sort Golka Dariusz
collection DOAJ
description <p>Abstract</p> <p>This short report discusses a case of neurofibroma containing floret-like multinucleated giant cells. This being the second such case in the literature. Floret-like multinucleated giant cells have been reported in gynaecomastia and neurofibroma in neurofibromatosis type 1. These cells have been reported in uncommon soft tissue tumours including pleomorphic lipoma, giant cell collagenoma, giant cell fibroblastoma and giant cell angiofibroma. We recommend these cells to be interpreted carefully keeping in mind the rare malignant change in neurofibromas. Immunohistochemistry would help in defining the nature of such cells.</p>
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spelling doaj.art-1034ae3ce4c047afa014158bc1b033352022-12-21T21:19:10ZengBMCDiagnostic Pathology1746-15962007-12-01214710.1186/1746-1596-2-47Floret-like multinucleated giant cells in neurofibromaGolka DariuszShaktawat Sameer<p>Abstract</p> <p>This short report discusses a case of neurofibroma containing floret-like multinucleated giant cells. This being the second such case in the literature. Floret-like multinucleated giant cells have been reported in gynaecomastia and neurofibroma in neurofibromatosis type 1. These cells have been reported in uncommon soft tissue tumours including pleomorphic lipoma, giant cell collagenoma, giant cell fibroblastoma and giant cell angiofibroma. We recommend these cells to be interpreted carefully keeping in mind the rare malignant change in neurofibromas. Immunohistochemistry would help in defining the nature of such cells.</p>http://www.diagnosticpathology.org/content/2/1/47
spellingShingle Golka Dariusz
Shaktawat Sameer
Floret-like multinucleated giant cells in neurofibroma
Diagnostic Pathology
title Floret-like multinucleated giant cells in neurofibroma
title_full Floret-like multinucleated giant cells in neurofibroma
title_fullStr Floret-like multinucleated giant cells in neurofibroma
title_full_unstemmed Floret-like multinucleated giant cells in neurofibroma
title_short Floret-like multinucleated giant cells in neurofibroma
title_sort floret like multinucleated giant cells in neurofibroma
url http://www.diagnosticpathology.org/content/2/1/47
work_keys_str_mv AT golkadariusz floretlikemultinucleatedgiantcellsinneurofibroma
AT shaktawatsameer floretlikemultinucleatedgiantcellsinneurofibroma