Proton currents constrain structural models of voltage sensor activation

Proton currents constrain structural models of voltage sensor activation

The Hv1 proton channel is evidently unique among voltage sensor domain proteins in mediating an intrinsic ‘aqueous’ H+ conductance (GAQ). Mutation of a highly conserved ‘gating charge’ residue in the S4 helix (R1H) confers a resting-state H+ ‘shuttle’ conductance (GSH) in VGCs and Ci VSP, and we now...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Aaron L Randolph, Younes Mokrab, Ashley L Bennett, Mark SP Sansom, Ian Scott Ramsey
स्वरूप:	लेख
भाषा:	English
प्रकाशित:	eLife Sciences Publications Ltd 2016-08-01
श्रृंखला:	eLife
विषय:	proton transport membrane channels channel gating voltage sensor protein structure
ऑनलाइन पहुंच:	https://elifesciences.org/articles/18017

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