Proton currents constrain structural models of voltage sensor activation
The Hv1 proton channel is evidently unique among voltage sensor domain proteins in mediating an intrinsic ‘aqueous’ H+ conductance (GAQ). Mutation of a highly conserved ‘gating charge’ residue in the S4 helix (R1H) confers a resting-state H+ ‘shuttle’ conductance (GSH) in VGCs and Ci VSP, and we now...
| Үндсэн зохиолчид: | , , , , |
|---|---|
| Формат: | Өгүүллэг |
| Хэл сонгох: | English |
| Хэвлэсэн: |
eLife Sciences Publications Ltd
2016-08-01
|
| Цуврал: | eLife |
| Нөхцлүүд: | |
| Онлайн хандалт: | https://elifesciences.org/articles/18017 |