Antibody response to oral biofilm is a biomarker for acute coronary syndrome in periodontal disease
This study finds that antibodies against antigens present in oral biofilm are potential biomarkers of acute coronary syndrome (ACS), the most severe form of coronary artery disease. By testing antibody response to periodontal pathogens, the authors find that patients with ACS have little or no immun...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-03-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-022-03122-4 |
| _version_ | 1818915615367233536 |
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| author | Mariliis Jaago Nadežda Pupina Annika Rähni Arno Pihlak Helle Sadam Nihal Engin Vrana Juha Sinisalo Pirkko Pussinen Kaia Palm |
| author_facet | Mariliis Jaago Nadežda Pupina Annika Rähni Arno Pihlak Helle Sadam Nihal Engin Vrana Juha Sinisalo Pirkko Pussinen Kaia Palm |
| author_sort | Mariliis Jaago |
| collection | DOAJ |
| description | This study finds that antibodies against antigens present in oral biofilm are potential biomarkers of acute coronary syndrome (ACS), the most severe form of coronary artery disease. By testing antibody response to periodontal pathogens, the authors find that patients with ACS have little or no immune response to a particular antigen epitope. |
| first_indexed | 2024-12-20T00:05:06Z |
| format | Article |
| id | doaj.art-103fd1cb45b946e5b202d73ba232ac95 |
| institution | Directory Open Access Journal |
| issn | 2399-3642 |
| language | English |
| last_indexed | 2024-12-20T00:05:06Z |
| publishDate | 2022-03-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Communications Biology |
| spelling | doaj.art-103fd1cb45b946e5b202d73ba232ac952022-12-21T20:00:40ZengNature PortfolioCommunications Biology2399-36422022-03-015111010.1038/s42003-022-03122-4Antibody response to oral biofilm is a biomarker for acute coronary syndrome in periodontal diseaseMariliis Jaago0Nadežda Pupina1Annika Rähni2Arno Pihlak3Helle Sadam4Nihal Engin Vrana5Juha Sinisalo6Pirkko Pussinen7Kaia Palm8Protobios LlcProtobios LlcProtobios LlcProtobios LlcProtobios LlcSpartha Medical, 14B Rue de la CanardiereHeart and Lung Center, Helsinki University Hospital, and Helsinki UniversityOral and Maxillofacial Diseases, University of HelsinkiProtobios LlcThis study finds that antibodies against antigens present in oral biofilm are potential biomarkers of acute coronary syndrome (ACS), the most severe form of coronary artery disease. By testing antibody response to periodontal pathogens, the authors find that patients with ACS have little or no immune response to a particular antigen epitope.https://doi.org/10.1038/s42003-022-03122-4 |
| spellingShingle | Mariliis Jaago Nadežda Pupina Annika Rähni Arno Pihlak Helle Sadam Nihal Engin Vrana Juha Sinisalo Pirkko Pussinen Kaia Palm Antibody response to oral biofilm is a biomarker for acute coronary syndrome in periodontal disease Communications Biology |
| title | Antibody response to oral biofilm is a biomarker for acute coronary syndrome in periodontal disease |
| title_full | Antibody response to oral biofilm is a biomarker for acute coronary syndrome in periodontal disease |
| title_fullStr | Antibody response to oral biofilm is a biomarker for acute coronary syndrome in periodontal disease |
| title_full_unstemmed | Antibody response to oral biofilm is a biomarker for acute coronary syndrome in periodontal disease |
| title_short | Antibody response to oral biofilm is a biomarker for acute coronary syndrome in periodontal disease |
| title_sort | antibody response to oral biofilm is a biomarker for acute coronary syndrome in periodontal disease |
| url | https://doi.org/10.1038/s42003-022-03122-4 |
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