Age-associated accumulation of B cells promotes macrophage inflammation and inhibits lipolysis in adipose tissue during sepsis

Age-associated accumulation of B cells promotes macrophage inflammation and inhibits lipolysis in adipose tissue during sepsis

Summary: Non-canonical lipolysis induced by inflammatory cytokines or Toll-like receptor ligands is required for the regulation of inflammation during endotoxemia and sepsis. Canonical lipolysis induced by catecholamines declines during aging due to factors including an expansion of lymphocytes, pro...

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Bibliographic Details
Main Authors: Anna Carey, Katie Nguyen, Pranathi Kandikonda, Victor Kruglov, Claire Bradley, Korbyn J.V. Dahlquist, Stephanie Cholensky, Whitney Swanson, Vladimir P. Badovinac, Thomas S. Griffith, Christina D. Camell
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Cell Reports
Subjects:
CP: Metabolism
CP: Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S221112472400295X

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