Impact of Parkinson’s Disease on Functional Mobility at Different Stages

IntroductionSpecific functional assessments to determine the progression of Parkinson’s Disease (PD) are important to slow down such progression and better plan rehabilitation. This study aimed to explore possible differences in the performance of different functional tasks included in a mobility te...

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Main Authors: Sara Mollà-Casanova, Jose Pedrero-Sánchez, Marta Inglés, Juan López-Pascual, Elena Muñoz-Gómez, Marta Aguilar-Rodríguez, Nuria Sempere-Rubio, Pilar Serra-Añó
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2022.935841/full
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author Sara Mollà-Casanova
Jose Pedrero-Sánchez
Marta Inglés
Juan López-Pascual
Elena Muñoz-Gómez
Marta Aguilar-Rodríguez
Nuria Sempere-Rubio
Pilar Serra-Añó
author_facet Sara Mollà-Casanova
Jose Pedrero-Sánchez
Marta Inglés
Juan López-Pascual
Elena Muñoz-Gómez
Marta Aguilar-Rodríguez
Nuria Sempere-Rubio
Pilar Serra-Añó
author_sort Sara Mollà-Casanova
collection DOAJ
description IntroductionSpecific functional assessments to determine the progression of Parkinson’s Disease (PD) are important to slow down such progression and better plan rehabilitation. This study aimed to explore possible differences in the performance of different functional tasks included in a mobility test using sensors embedded in an Android device, in people at different PD stages.Materials and MethodsEighty-seven participants with PD agreed to participate in this cross-sectional study. They were assessed once using an inertial sensor and variables related to functional status were recorded (i.e., MLDisp, APDisp, DispA, Vrange, MLRange, PTurnSit, PStand, TTime, and RTime).ResultsThere was significant impairment of the vertical range during gait between stages I and II. Further, when stages II and III were compared, the sit-to-stand power was significantly impaired, and the total time required to complete the test increased significantly (p < 0.05). Even more significant differences were obtained when stages I and III were compared, in particular, dysfunction in postural control, vertical range, sit to stand power and total time. Finally, there were no significant differences between stages in the medial-lateral displacements and reaction time (p > 0.05).ConclusionFunctional mobility becomes more significantly impaired in the PD population as the PD stages progress. This implies impaired postural control, decreased ability to sit down or stand up from a chair, increased metabolic cost during walking, and overall slowing-down of motor function.
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spelling doaj.art-1043db5009e44448aabb570b2f9564412022-12-22T00:18:57ZengFrontiers Media S.A.Frontiers in Aging Neuroscience1663-43652022-06-011410.3389/fnagi.2022.935841935841Impact of Parkinson’s Disease on Functional Mobility at Different StagesSara Mollà-Casanova0Jose Pedrero-Sánchez1Marta Inglés2Juan López-Pascual3Elena Muñoz-Gómez4Marta Aguilar-Rodríguez5Nuria Sempere-Rubio6Pilar Serra-Añó7UBIC, Department of Physiotherapy, Faculty of Physiotherapy, Universitat de Valéncia, Valencia, SpainInstituto de Biomecánica de Valencia, Universidad Politécnica de Valencia, Valencia, SpainUBIC, Department of Physiotherapy, Faculty of Physiotherapy, Universitat de Valéncia, Valencia, SpainInstituto de Biomecánica de Valencia, Universidad Politécnica de Valencia, Valencia, SpainUBIC, Department of Physiotherapy, Faculty of Physiotherapy, Universitat de Valéncia, Valencia, SpainUBIC, Department of Physiotherapy, Faculty of Physiotherapy, Universitat de Valéncia, Valencia, SpainUBIC, Department of Physiotherapy, Faculty of Physiotherapy, Universitat de Valéncia, Valencia, SpainUBIC, Department of Physiotherapy, Faculty of Physiotherapy, Universitat de Valéncia, Valencia, SpainIntroductionSpecific functional assessments to determine the progression of Parkinson’s Disease (PD) are important to slow down such progression and better plan rehabilitation. This study aimed to explore possible differences in the performance of different functional tasks included in a mobility test using sensors embedded in an Android device, in people at different PD stages.Materials and MethodsEighty-seven participants with PD agreed to participate in this cross-sectional study. They were assessed once using an inertial sensor and variables related to functional status were recorded (i.e., MLDisp, APDisp, DispA, Vrange, MLRange, PTurnSit, PStand, TTime, and RTime).ResultsThere was significant impairment of the vertical range during gait between stages I and II. Further, when stages II and III were compared, the sit-to-stand power was significantly impaired, and the total time required to complete the test increased significantly (p < 0.05). Even more significant differences were obtained when stages I and III were compared, in particular, dysfunction in postural control, vertical range, sit to stand power and total time. Finally, there were no significant differences between stages in the medial-lateral displacements and reaction time (p > 0.05).ConclusionFunctional mobility becomes more significantly impaired in the PD population as the PD stages progress. This implies impaired postural control, decreased ability to sit down or stand up from a chair, increased metabolic cost during walking, and overall slowing-down of motor function.https://www.frontiersin.org/articles/10.3389/fnagi.2022.935841/fullParkinson’s diseasefunctional assessmentFallSkipseverity of Parkinson’sHoen and Yahr stages
spellingShingle Sara Mollà-Casanova
Jose Pedrero-Sánchez
Marta Inglés
Juan López-Pascual
Elena Muñoz-Gómez
Marta Aguilar-Rodríguez
Nuria Sempere-Rubio
Pilar Serra-Añó
Impact of Parkinson’s Disease on Functional Mobility at Different Stages
Frontiers in Aging Neuroscience
Parkinson’s disease
functional assessment
FallSkip
severity of Parkinson’s
Hoen and Yahr stages
title Impact of Parkinson’s Disease on Functional Mobility at Different Stages
title_full Impact of Parkinson’s Disease on Functional Mobility at Different Stages
title_fullStr Impact of Parkinson’s Disease on Functional Mobility at Different Stages
title_full_unstemmed Impact of Parkinson’s Disease on Functional Mobility at Different Stages
title_short Impact of Parkinson’s Disease on Functional Mobility at Different Stages
title_sort impact of parkinson s disease on functional mobility at different stages
topic Parkinson’s disease
functional assessment
FallSkip
severity of Parkinson’s
Hoen and Yahr stages
url https://www.frontiersin.org/articles/10.3389/fnagi.2022.935841/full
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