Immunology of amyotrophic lateral sclerosis – role of the innate and adaptive immunity

Immunology of amyotrophic lateral sclerosis – role of the innate and adaptive immunity

This review aims to summarize the latest evidence about the role of innate and adaptive immunity in Amyotrophic Lateral Sclerosis (ALS). ALS is a devastating neurodegenerative disease affecting upper and lower motor neurons, which involves essential cells of the immune system that play a basic role...

Full description

Bibliographic Details
Main Authors:	Stefan Mimic, Başak Aru, Cemil Pehlivanoğlu, Hadi Sleiman, Pavle R. Andjus, Gülderen Yanıkkaya Demirel
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-11-01
Series:	Frontiers in Neuroscience
Subjects:	amyotrophic lateral sclerosis neuroimmunology and neuropathy innate immune system adaptive immune system neurodegeneration
Online Access:	https://www.frontiersin.org/articles/10.3389/fnins.2023.1277399/full

Similar Items

The role of the innate immune system in ALS
by: Sudarshan ePhani, et al.
Published: (2012-08-01)

Advances on Cellular Clonotypic Immunity in Amyotrophic Lateral Sclerosis
by: Giuseppe Schirò, et al.
Published: (2022-10-01)

Immunological context of brain injury
by: N. G. Plekhova, et al.
Published: (2021-03-01)

A potential area of use for immune checkpoint inhibitors: Targeting bone marrow microenvironment in acute myeloid leukemia
by: Başak Aru, et al.
Published: (2023-01-01)

A prospective longitudinal study on the microbiota composition in amyotrophic lateral sclerosis
by: Diana Di Gioia, et al.
Published: (2020-06-01)

Sport and risk of amyotrophic lateral sclerosis
by: Joanna Iłżecka
Published: (2019-01-01)

Sport and risk of amyotrophic lateral sclerosis
by: Joanna Iłżecka
Published: (2019-01-01)

Sport and risk of amyotrophic lateral sclerosis
by: Joanna Iłżecka
Published: (2019-01-01)

Therapeutic Treatment of Superoxide Dismutase 1 (G93A) Amyotrophic Lateral Sclerosis Model Mice with Medical Ozone Decelerates Trigeminal Motor Neuron Degeneration, Attenuates Microglial Proliferation, and Preserves Monocyte Levels in Mesenteric Lymph Nodes
by: Michael Bette, et al.
Published: (2022-03-01)

Innate immune sensors for detecting nucleic acids during infection
by: Ghoreshi Zohreh-alsadat, et al.
Published: (2022-06-01)

Aberrant NLRP3 Inflammasome Activation Ignites the Fire of Inflammation in Neuromuscular Diseases
by: Christine Péladeau, et al.
Published: (2021-06-01)

Immune checkpoint inhibitors in the treatment of hepatocellular carcinoma
by: Zeynep Akbulut, et al.
Published: (2024-04-01)

Dysregulated Monocyte and Neutrophil Functional Phenotype in Infants With Neonatal Encephalopathy Requiring Therapeutic Hypothermia
by: Mary Isabel O'Dea, et al.
Published: (2021-02-01)

Peripheral and Central Nervous System Immune Response Crosstalk in Amyotrophic Lateral Sclerosis
by: Zhouyang Liu, et al.
Published: (2020-06-01)

Dysautonomia in Amyotrophic Lateral Sclerosis
by: Alexandra L. Oprisan, et al.
Published: (2023-10-01)

Potential of activated microglia as a source of dysregulated extracellular microRNAs contributing to neurodegeneration in amyotrophic lateral sclerosis
by: Eleni Christoforidou, et al.
Published: (2020-04-01)

Specificity of Adaptive Immune Responses in Central Nervous System Health, Aging and Diseases
by: Chiara Rickenbach, et al.
Published: (2022-01-01)

The Cutaneous Wound Innate Immunological Microenvironment
by: Stephen Kirchner, et al.
Published: (2020-11-01)

Neuroimmune Crosstalk Between the Peripheral and the Central Immune System in Amyotrophic Lateral Sclerosis
by: Weiyi Yu, et al.
Published: (2022-05-01)

Serum programmed cell death proteins in amyotrophic lateral sclerosis
by: David R. Beers, et al.
Published: (2021-03-01)

Concurrent multiple sclerosis and amyotrophic lateral sclerosis: where inflammation and neurodegeneration meet?
by: Li Grace, et al.
Published: (2012-01-01)

Correlation between leukocyte phenotypes and prognosis of amyotrophic lateral sclerosis
by: Can Cui, et al.
Published: (2022-03-01)

Current view and perspectives in amyotrophic lateral sclerosis
by: Stéphane Mathis, et al.
Published: (2017-01-01)

Neural and neuroendocrine mechanisms in host defense and autoimmunity /
by: Welsh, C.Jane, et al.
Published: (2006)

Iron Status May Not Affect Amyotrophic Lateral Sclerosis: A Mendelian Randomization Study
by: Jiahao Cai, et al.
Published: (2021-03-01)

Complement Profiles in Patients with Amyotrophic Lateral Sclerosis: A Prospective Observational Cohort Study
by: Kjældgaard AL, et al.
Published: (2021-03-01)

The Cell Autonomous and Non-Cell Autonomous Aspects of Neuronal Vulnerability and Resilience in Amyotrophic Lateral Sclerosis
by: Christoph Schweingruber, et al.
Published: (2022-08-01)

The Peripheral Immune System and Amyotrophic Lateral Sclerosis
by: Pamela A. McCombe, et al.
Published: (2020-04-01)

Amyotrophic Lateral Sclerosis and Serum Lipid Level Association: A Systematic Review and Meta-Analytic Study
by: Teresa Pardo-Moreno, et al.
Published: (2023-05-01)

Chitotriosidase, a biomarker of amyotrophic lateral sclerosis, accentuates neurodegeneration in spinal motor neurons through neuroinflammation
by: Anu Mary Varghese, et al.
Published: (2020-08-01)

Hypothalamus and amyotrophic lateral sclerosis: potential implications in sleep disorders
by: Valentina Gnoni, et al.
Published: (2023-07-01)

Adjuvant Lineage-Negative Cell Therapy as a Potential Silencer of the Complement-Mediated Immune System in ALS Patients
by: Anna Sobuś, et al.
Published: (2021-11-01)

Tuberculin responses after BCG vaccination predict amyotrophic lateral sclerosis risk
by: Ola Nakken, et al.
Published: (2023-12-01)

New perspectives on cytoskeletal dysregulation and mitochondrial mislocalization in amyotrophic lateral sclerosis
by: Frances Theunissen, et al.
Published: (2021-11-01)

Kynurenine Pathway Metabolites as Biomarkers for Amyotrophic Lateral Sclerosis
by: Vanessa X. Tan, et al.
Published: (2019-09-01)

Pathophysiology of ion channels in amyotrophic lateral sclerosis
by: Robin N. Stringer, et al.
Published: (2023-12-01)

Innate Immunity in Calcinosis Cutis
by: Simon W. Jiang, et al.
Published: (2022-07-01)

Kinesitherapy in amyotrophic lateral sclerosis
by: Joanna Iłżecka
Published: (2017-12-01)

Kinesitherapy in amyotrophic lateral sclerosis
by: Joanna Iłżecka
Published: (2017-12-01)

Innate and intrinsic immunity in planarians
by: L Gao, et al.
Published: (2017-11-01)