Recovery of a triazole-resistant Aspergillus fumigatus in respiratory specimen of COVID-19 patient in ICU – A case report
Although invasive pulmonary aspergillosis (IPA) is typically described in immunocompromised host, patient with severe influenzae can develop IPA. Similarly, patients with severe COVID-19 complicated with IPA are increasingly reported. Here, we describe a case of invasive aspergillosis with triazole-...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2021-03-01
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| Series: | Medical Mycology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211753920300439 |
| _version_ | 1818411784103526400 |
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| author | Théo Ghelfenstein-Ferreira Anastasia Saade Alexandre Alanio Stéphane Bretagne Raffael Araujo de Castro Samia Hamane Elie Azoulay Swann Bredin Sarah Dellière |
| author_facet | Théo Ghelfenstein-Ferreira Anastasia Saade Alexandre Alanio Stéphane Bretagne Raffael Araujo de Castro Samia Hamane Elie Azoulay Swann Bredin Sarah Dellière |
| author_sort | Théo Ghelfenstein-Ferreira |
| collection | DOAJ |
| description | Although invasive pulmonary aspergillosis (IPA) is typically described in immunocompromised host, patient with severe influenzae can develop IPA. Similarly, patients with severe COVID-19 complicated with IPA are increasingly reported. Here, we describe a case of invasive aspergillosis with triazole-resistant A. fumigatus (TR34/L98H mutation) in a 56-year-old patient with COVID-19 in intensive care unit. This report highlights the need to define the available tools for diagnosis of invasive aspergillosis in severe COVID-19 patients. |
| first_indexed | 2024-12-14T10:36:55Z |
| format | Article |
| id | doaj.art-104dca6697724e8095b10b5fd504dcd1 |
| institution | Directory Open Access Journal |
| issn | 2211-7539 |
| language | English |
| last_indexed | 2024-12-14T10:36:55Z |
| publishDate | 2021-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Medical Mycology Case Reports |
| spelling | doaj.art-104dca6697724e8095b10b5fd504dcd12022-12-21T23:05:52ZengElsevierMedical Mycology Case Reports2211-75392021-03-01311518Recovery of a triazole-resistant Aspergillus fumigatus in respiratory specimen of COVID-19 patient in ICU – A case reportThéo Ghelfenstein-Ferreira0Anastasia Saade1Alexandre Alanio2Stéphane Bretagne3Raffael Araujo de Castro4Samia Hamane5Elie Azoulay6Swann Bredin7Sarah Dellière8Laboratoire de Parasitologie – Mycologie, Hôpital Saint-Louis (AP-HP), Université de Paris, France; Corresponding author. Saint-Louis Hospital, Paris, France, 1 avenue Claude Vellefaux, 75010, Paris, France.Médecine Intensive et Réanimation, Hôpital Saint-Louis (AP-HP), Université de Paris, FranceLaboratoire de Parasitologie – Mycologie, Hôpital Saint-Louis (AP-HP), Université de Paris, France; Unité de Mycologie Moléculaire, Institut Pasteur, CNRS URA 3012, Centre National de Référence des Mycoses Invasives et des Antifongiques, URA, 3012, Paris, FranceLaboratoire de Parasitologie – Mycologie, Hôpital Saint-Louis (AP-HP), Université de Paris, France; Unité de Mycologie Moléculaire, Institut Pasteur, CNRS URA 3012, Centre National de Référence des Mycoses Invasives et des Antifongiques, URA, 3012, Paris, FranceUnité de Mycologie Moléculaire, Institut Pasteur, CNRS URA 3012, Centre National de Référence des Mycoses Invasives et des Antifongiques, URA, 3012, Paris, FranceLaboratoire de Parasitologie – Mycologie, Hôpital Saint-Louis (AP-HP), Université de Paris, FranceMédecine Intensive et Réanimation, Hôpital Saint-Louis (AP-HP), Université de Paris, FranceMédecine Intensive et Réanimation, Hôpital Saint-Louis (AP-HP), Université de Paris, FranceLaboratoire de Parasitologie – Mycologie, Hôpital Saint-Louis (AP-HP), Université de Paris, FranceAlthough invasive pulmonary aspergillosis (IPA) is typically described in immunocompromised host, patient with severe influenzae can develop IPA. Similarly, patients with severe COVID-19 complicated with IPA are increasingly reported. Here, we describe a case of invasive aspergillosis with triazole-resistant A. fumigatus (TR34/L98H mutation) in a 56-year-old patient with COVID-19 in intensive care unit. This report highlights the need to define the available tools for diagnosis of invasive aspergillosis in severe COVID-19 patients.http://www.sciencedirect.com/science/article/pii/S2211753920300439AspergillosisCOVID-19ICUTriazole-resistanceCoronavirusSARS-CoV2 |
| spellingShingle | Théo Ghelfenstein-Ferreira Anastasia Saade Alexandre Alanio Stéphane Bretagne Raffael Araujo de Castro Samia Hamane Elie Azoulay Swann Bredin Sarah Dellière Recovery of a triazole-resistant Aspergillus fumigatus in respiratory specimen of COVID-19 patient in ICU – A case report Medical Mycology Case Reports Aspergillosis COVID-19 ICU Triazole-resistance Coronavirus SARS-CoV2 |
| title | Recovery of a triazole-resistant Aspergillus fumigatus in respiratory specimen of COVID-19 patient in ICU – A case report |
| title_full | Recovery of a triazole-resistant Aspergillus fumigatus in respiratory specimen of COVID-19 patient in ICU – A case report |
| title_fullStr | Recovery of a triazole-resistant Aspergillus fumigatus in respiratory specimen of COVID-19 patient in ICU – A case report |
| title_full_unstemmed | Recovery of a triazole-resistant Aspergillus fumigatus in respiratory specimen of COVID-19 patient in ICU – A case report |
| title_short | Recovery of a triazole-resistant Aspergillus fumigatus in respiratory specimen of COVID-19 patient in ICU – A case report |
| title_sort | recovery of a triazole resistant aspergillus fumigatus in respiratory specimen of covid 19 patient in icu a case report |
| topic | Aspergillosis COVID-19 ICU Triazole-resistance Coronavirus SARS-CoV2 |
| url | http://www.sciencedirect.com/science/article/pii/S2211753920300439 |
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