DNM3OS/miR-127-5p/CDH11, activates Wnt3a/β-catenin/LEF-1 pathway to form a positive feedback and aggravate spine facet joint osteoarthritis

DNM3OS/miR-127-5p/CDH11, activates Wnt3a/β-catenin/LEF-1 pathway to form a positive feedback and aggravate spine facet joint osteoarthritis

Spinal facet joint osteoarthritis (FJOA) is an OA disease with pathogenesis and progression uncovered. Our present study was performed to elucidate the role of DNM3OS on spinal FJOA. In this study, spine facet joint tissue of patients were collected. In vitro and in vivo models were constructed with...

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Bibliographic Details
Main Authors: Jing Wang, Zhenyu Yang, Xiuming He, Yeyang Wang, Dixin Luo, Wangyang Xu, Hongtao Zhang, Xiaozhong Zhou
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2024-06-01
Series:Non-coding RNA Research
Subjects:
ceRNA network
Spinal facet joint osteoarthritis
DNM3OS
miR-127-5p
Wnt/β-Catenin/LEF-1
Online Access:http://www.sciencedirect.com/science/article/pii/S2468054024000088

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