Cutaneous papules in a patient with AIDS
During the past decade or so, the incidence of syphilis has increased in most parts of the world. In some urban regions, a coinfection with human immunodeficiency virus is disclosed in nearly 50% of the cases. Owing to the polymorphism of the lesions, the clinical diagnosis may be puzzling. The homi...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
PAGEPress Publications
2010-01-01
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| Series: | Dermatology Reports |
| Subjects: | |
| Online Access: | http://www.pagepress.org/journals/index.php/dr/article/view/1417 |
| Summary: | During the past decade or so, the incidence of syphilis has increased in most parts of the world. In some urban regions, a coinfection with human immunodeficiency virus is disclosed in nearly 50% of the cases. Owing to the polymorphism of the lesions, the clinical diagnosis may be puzzling. The homing patterns and migration paths of <em>Treponema pallidum</em> in the skin during early syphilis represent the preliminary steps preceding dissemination to other organs. Immunohistochemistry directed to <em>T. pallidum</em> is a convenient means for reaching the diagnosis and for exploring the dissemination process. The present case illustrates the dermal clustering and the vascular spread of <em>T. pallidum</em> in a woman with acquired immuno deficiency syndrome. |
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| ISSN: | 2036-7392 2036-7406 |