Spatially resolved transcriptomics reveals pro-inflammatory fibroblast involved in lymphocyte recruitment through CXCL8 and CXCL10

Spatially resolved transcriptomics reveals pro-inflammatory fibroblast involved in lymphocyte recruitment through CXCL8 and CXCL10

The interplay among different cells in a tissue is essential for maintaining homeostasis. Although disease states have been traditionally attributed to individual cell types, increasing evidence and new therapeutic options have demonstrated the primary role of multicellular functions to understand h...

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Bibliographic Details
Main Authors: Ana J Caetano, Yushi Redhead, Farah Karim, Pawan Dhami, Shichina Kannambath, Rosamond Nuamah, Ana A Volponi, Luigi Nibali, Veronica Booth, Eleanor M D'Agostino, Paul T Sharpe
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-01-01
Series:eLife
Subjects:
gingiva
fibroblast
inflammation
oral mucosa
spatial genomics
periodontal disease
Online Access:https://elifesciences.org/articles/81525

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