Modulating OFC Activity With tDCS Alters Regret About Human Decision-Making
Regret is a common emotion in daily life. Humans always regret their decision-making choices if the chosen outcome is bad. Neuroscientific studies suggest that the orbitofrontal cortex (OFC) influences feelings of regret. We used a transcranial direct current stimulation (tDCS) device to study the r...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2021-09-01
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| Series: | Frontiers in Psychology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpsyg.2021.706962/full |
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| author | Ping Yu Ping Yu Xinbo Lu Xinbo Lu Yuyou Chen Yuyou Chen Hang Ye Hang Ye Lulu Zeng Lulu Zeng Wenmin Guo Wenmin Guo |
| author_facet | Ping Yu Ping Yu Xinbo Lu Xinbo Lu Yuyou Chen Yuyou Chen Hang Ye Hang Ye Lulu Zeng Lulu Zeng Wenmin Guo Wenmin Guo |
| author_sort | Ping Yu |
| collection | DOAJ |
| description | Regret is a common emotion in daily life. Humans always regret their decision-making choices if the chosen outcome is bad. Neuroscientific studies suggest that the orbitofrontal cortex (OFC) influences feelings of regret. We used a transcranial direct current stimulation (tDCS) device to study the role of regret in participants’ decision-making by modulating the activity of the OFC. The two-wheel-of-fortune gamble task was used in our experimental design, and we asked the participants to rate their feelings of regret after the computer presented the obtained and unobtained outcomes. The experimental results revealed that the effect of stimulation type was significant, which indicated that the influence of the OFC in regret was modulated by tDCS. Furthermore, based on post hoc analyses (Bonferroni), regret was lower in those who received left anodal/right cathodal stimulation than in those who received sham stimulation, which revealed that modulating the activity of the OFC reduced the emotional intensity of regret. In addition, an inverted U-shaped curve characterized the mean ratings of regret over time. |
| first_indexed | 2024-12-17T01:14:30Z |
| format | Article |
| id | doaj.art-105f61413b6e4e71949be986504a5c42 |
| institution | Directory Open Access Journal |
| issn | 1664-1078 |
| language | English |
| last_indexed | 2024-12-17T01:14:30Z |
| publishDate | 2021-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Psychology |
| spelling | doaj.art-105f61413b6e4e71949be986504a5c422022-12-21T22:09:02ZengFrontiers Media S.A.Frontiers in Psychology1664-10782021-09-011210.3389/fpsyg.2021.706962706962Modulating OFC Activity With tDCS Alters Regret About Human Decision-MakingPing Yu0Ping Yu1Xinbo Lu2Xinbo Lu3Yuyou Chen4Yuyou Chen5Hang Ye6Hang Ye7Lulu Zeng8Lulu Zeng9Wenmin Guo10Wenmin Guo11Center for Economic Behavior and Decision-Making (CEBD), Zhejiang University of Finance and Economics, Hangzhou, ChinaSchool of Economics, Zhejiang University of Finance and Economics, Hangzhou, ChinaSchool of Economics, Zhejiang University of Finance and Economics, Hangzhou, ChinaSchool of Economics, Jiaxing University, Jiaxing, ChinaCenter for Economic Behavior and Decision-Making (CEBD), Zhejiang University of Finance and Economics, Hangzhou, ChinaSchool of Economics, Zhejiang University of Finance and Economics, Hangzhou, ChinaCenter for Economic Behavior and Decision-Making (CEBD), Zhejiang University of Finance and Economics, Hangzhou, ChinaSchool of Economics, Zhejiang University of Finance and Economics, Hangzhou, ChinaCenter for Economic Behavior and Decision-Making (CEBD), Zhejiang University of Finance and Economics, Hangzhou, ChinaSchool of Economics, Zhejiang University of Finance and Economics, Hangzhou, ChinaCenter for Economic Behavior and Decision-Making (CEBD), Zhejiang University of Finance and Economics, Hangzhou, ChinaSchool of Economics, Zhejiang University of Finance and Economics, Hangzhou, ChinaRegret is a common emotion in daily life. Humans always regret their decision-making choices if the chosen outcome is bad. Neuroscientific studies suggest that the orbitofrontal cortex (OFC) influences feelings of regret. We used a transcranial direct current stimulation (tDCS) device to study the role of regret in participants’ decision-making by modulating the activity of the OFC. The two-wheel-of-fortune gamble task was used in our experimental design, and we asked the participants to rate their feelings of regret after the computer presented the obtained and unobtained outcomes. The experimental results revealed that the effect of stimulation type was significant, which indicated that the influence of the OFC in regret was modulated by tDCS. Furthermore, based on post hoc analyses (Bonferroni), regret was lower in those who received left anodal/right cathodal stimulation than in those who received sham stimulation, which revealed that modulating the activity of the OFC reduced the emotional intensity of regret. In addition, an inverted U-shaped curve characterized the mean ratings of regret over time.https://www.frontiersin.org/articles/10.3389/fpsyg.2021.706962/fullregretdecision-makingorbitofrontal cortextranscranial direct current stimulationcounterfactual thinking |
| spellingShingle | Ping Yu Ping Yu Xinbo Lu Xinbo Lu Yuyou Chen Yuyou Chen Hang Ye Hang Ye Lulu Zeng Lulu Zeng Wenmin Guo Wenmin Guo Modulating OFC Activity With tDCS Alters Regret About Human Decision-Making Frontiers in Psychology regret decision-making orbitofrontal cortex transcranial direct current stimulation counterfactual thinking |
| title | Modulating OFC Activity With tDCS Alters Regret About Human Decision-Making |
| title_full | Modulating OFC Activity With tDCS Alters Regret About Human Decision-Making |
| title_fullStr | Modulating OFC Activity With tDCS Alters Regret About Human Decision-Making |
| title_full_unstemmed | Modulating OFC Activity With tDCS Alters Regret About Human Decision-Making |
| title_short | Modulating OFC Activity With tDCS Alters Regret About Human Decision-Making |
| title_sort | modulating ofc activity with tdcs alters regret about human decision making |
| topic | regret decision-making orbitofrontal cortex transcranial direct current stimulation counterfactual thinking |
| url | https://www.frontiersin.org/articles/10.3389/fpsyg.2021.706962/full |
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