LIVER HAEMANGIOMA IN NEONATES – REVIEW OF THE LITERATURE AND RETROSPECTIVE ANALYSIS OF CLINICAL CHARACTERISTICS IN NEONATES BETWEEN 2010 AND 2020
Haemangiomas are benign vascular tumours that usually appear in infants. Most often they occur on the skin, but visceral, predominantly liver, haemangiomas, are also possible. During the last decade, due to rapidly increasing knowledge of genetic and histopathological markers, the nomenclature of th...
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| Format: | Article |
| Language: | Slovenian |
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The Society for Children with Metabolic Disorders
2022-03-01
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| Series: | Slovenska pediatrija |
| Subjects: | |
| Online Access: |
http://www.slovenskapediatrija.si/Portals/0/Clanki/2022/Slovpediatr-2022-1-02en.pdf
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| _version_ | 1828773068959383552 |
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| author | Nina Lah Mojca Glušič Orjana Velikonja Jana Lozar Krivec |
| author_facet | Nina Lah Mojca Glušič Orjana Velikonja Jana Lozar Krivec |
| author_sort | Nina Lah |
| collection | DOAJ |
| description | Haemangiomas are benign vascular tumours that usually appear in infants. Most often they occur on the skin, but visceral, predominantly liver, haemangiomas, are also possible. During the last decade, due to rapidly increasing knowledge of genetic and histopathological markers, the nomenclature of these lesions has become more standardised, followed by more consistent management and new treatment methods. In the paper, we describe liver haemangiomas, which can be divided into infantile and congenital forms. These can be differentiated by their clinical course, complications and treatment. Knowing the exact diagnosis and the course of the disease are crucial because lesions can rarely cause significant complications that require appropriate treatment. Reports of the effective treatment of liver haemangiomas with propranolol are found in the literature.
At the neonatology department of the University Medical Centre Ljubljana, 15 neonates with liver haemangiomas were evaluated during a 10-year-period, four of whom were treated with propranolol. With this treatment, symptom relief was achieved in three of the patients and gradual regression of the haemangioma in all four. |
| first_indexed | 2024-12-11T14:55:17Z |
| format | Article |
| id | doaj.art-1068ab58cc1245c8b37452607cdf5b4e |
| institution | Directory Open Access Journal |
| issn | 1318-4423 2712-3960 |
| language | Slovenian |
| last_indexed | 2024-12-11T14:55:17Z |
| publishDate | 2022-03-01 |
| publisher | The Society for Children with Metabolic Disorders |
| record_format | Article |
| series | Slovenska pediatrija |
| spelling | doaj.art-1068ab58cc1245c8b37452607cdf5b4e2022-12-22T01:01:19ZslvThe Society for Children with Metabolic DisordersSlovenska pediatrija1318-44232712-39602022-03-0129181610.38031/slovpediatr-2022-1-02en13184423LIVER HAEMANGIOMA IN NEONATES – REVIEW OF THE LITERATURE AND RETROSPECTIVE ANALYSIS OF CLINICAL CHARACTERISTICS IN NEONATES BETWEEN 2010 AND 2020Nina Lah0Mojca Glušič1Orjana Velikonja2Jana Lozar Krivec3 ZD Slovenj Gradec, Slovenj Gradec, Slovenija Služba za radiologijo, Pediatrična klinika, Univerzitetni klinični center Ljubljana, Ljubljana, Slovenija Klinični oddelek za otroško hematologijo in onkologijo, Pediatrična klinika, Univerzitetni klinični center Ljubljana, Ljubljana, Slovenija Klinični oddelek za neonatologijo, Pediatrična klinika, Univerzitetni klinični center Ljubljana, Ljubljana, Slovenija Haemangiomas are benign vascular tumours that usually appear in infants. Most often they occur on the skin, but visceral, predominantly liver, haemangiomas, are also possible. During the last decade, due to rapidly increasing knowledge of genetic and histopathological markers, the nomenclature of these lesions has become more standardised, followed by more consistent management and new treatment methods. In the paper, we describe liver haemangiomas, which can be divided into infantile and congenital forms. These can be differentiated by their clinical course, complications and treatment. Knowing the exact diagnosis and the course of the disease are crucial because lesions can rarely cause significant complications that require appropriate treatment. Reports of the effective treatment of liver haemangiomas with propranolol are found in the literature. At the neonatology department of the University Medical Centre Ljubljana, 15 neonates with liver haemangiomas were evaluated during a 10-year-period, four of whom were treated with propranolol. With this treatment, symptom relief was achieved in three of the patients and gradual regression of the haemangioma in all four. http://www.slovenskapediatrija.si/Portals/0/Clanki/2022/Slovpediatr-2022-1-02en.pdf haemangiomaliverpropranololtreatmentceus |
| spellingShingle | Nina Lah Mojca Glušič Orjana Velikonja Jana Lozar Krivec LIVER HAEMANGIOMA IN NEONATES – REVIEW OF THE LITERATURE AND RETROSPECTIVE ANALYSIS OF CLINICAL CHARACTERISTICS IN NEONATES BETWEEN 2010 AND 2020 Slovenska pediatrija haemangioma liver propranolol treatment ceus |
| title | LIVER HAEMANGIOMA IN NEONATES – REVIEW OF THE LITERATURE AND RETROSPECTIVE ANALYSIS OF CLINICAL CHARACTERISTICS IN NEONATES BETWEEN 2010 AND 2020 |
| title_full | LIVER HAEMANGIOMA IN NEONATES – REVIEW OF THE LITERATURE AND RETROSPECTIVE ANALYSIS OF CLINICAL CHARACTERISTICS IN NEONATES BETWEEN 2010 AND 2020 |
| title_fullStr | LIVER HAEMANGIOMA IN NEONATES – REVIEW OF THE LITERATURE AND RETROSPECTIVE ANALYSIS OF CLINICAL CHARACTERISTICS IN NEONATES BETWEEN 2010 AND 2020 |
| title_full_unstemmed | LIVER HAEMANGIOMA IN NEONATES – REVIEW OF THE LITERATURE AND RETROSPECTIVE ANALYSIS OF CLINICAL CHARACTERISTICS IN NEONATES BETWEEN 2010 AND 2020 |
| title_short | LIVER HAEMANGIOMA IN NEONATES – REVIEW OF THE LITERATURE AND RETROSPECTIVE ANALYSIS OF CLINICAL CHARACTERISTICS IN NEONATES BETWEEN 2010 AND 2020 |
| title_sort | liver haemangioma in neonates review of the literature and retrospective analysis of clinical characteristics in neonates between 2010 and 2020 |
| topic | haemangioma liver propranolol treatment ceus |
| url |
http://www.slovenskapediatrija.si/Portals/0/Clanki/2022/Slovpediatr-2022-1-02en.pdf
|
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